Relationship between the degree of early CgR, the CCgR rate at 2 years, and EFS at 42 months in IRIS study172 ,183
Time of treatment and cytogenetic response . | Probability of CCgR at 2 y, % . | EFS at 42 mo, % . |
|---|---|---|
| 3 mo | ||
| Partial | 90 | NAV |
| Minor | 60 | NAV |
| Minimal/none | 50 | NAV |
| 6 mo | ||
| Complete/partial | NAP/80 | 95 |
| Minor or minimal/none | 50/15 | 75 |
| 12 mo | ||
| Complete/partial | NAP/50 | 90 |
| Minor, minimal, or none | <20 | 65 |
Time of treatment and cytogenetic response . | Probability of CCgR at 2 y, % . | EFS at 42 mo, % . |
|---|---|---|
| 3 mo | ||
| Partial | 90 | NAV |
| Minor | 60 | NAV |
| Minimal/none | 50 | NAV |
| 6 mo | ||
| Complete/partial | NAP/80 | 95 |
| Minor or minimal/none | 50/15 | 75 |
| 12 mo | ||
| Complete/partial | NAP/50 | 90 |
| Minor, minimal, or none | <20 | 65 |
From the same study172,183 it was reported that after 54 months, survival free from progression to AP/BC was 97% for the patients with a CCgR at 12 months, 95% for those with a partial CgR, and 81% for those who at 12 months had achieved less than a partial CgR.58
NAP indicates not applicable, NAV indicates not available.