Table 2.

Demographic, clinical, and laboratory characteristics of patients with solitary plasmacytoma of bone for whom an FLC ratio was available at the time of diagnosis (N = 116)



FLC ratio

Characteristic
Abnormal
Normal
P
Sex, no. (%)    .63  
    Male   37 (68.5)   45 (72.6)   
    Female   17 (31.5)   17 (27.4)   
Age at diagnosis, y    .74  
    Median   61.5   59.5   
    Range   26.0-93.0   30.0-86.0   
Fracture, no. (%)    .96  
    Yes   11 (20.5)   12 (20.0)   
    No   43 (79.6)   48 (80.0)   
Hemoglobin, g/L    .53  
    Median   133   138   
    Range   (95-170)   (87-170)   
Serum monoclonal protein, no. (%)    .32  
    Positive   37 (68.5)   37 (59.7)   
    Negative   17 (31.5)   25 (40.3)   
Serum M spike, g/dL    .04  
    Median   1.0   0.3   
    Range   0.0-3.0   0.0-2.6   
Urine monoclonal protein, no. (%)    < .001  
    Positive   31 (60.8)   11 (20.4)   
    Negative   20 (39.2)   43 (79.6)   
Urine M spike, g/24 h    .58  
    Median   0.0   0.0   
    Range   0.0-0.2   0.0-0.2   
Reduction in uninvolved Igs, no. (%)    .19  
    0   15 (51.7)   21 (72.4)   
    1   10 (34.5)   7 (24.1)   
    2
 
1 (3.4)
 
4 (13.8)
 

 


FLC ratio

Characteristic
Abnormal
Normal
P
Sex, no. (%)    .63  
    Male   37 (68.5)   45 (72.6)   
    Female   17 (31.5)   17 (27.4)   
Age at diagnosis, y    .74  
    Median   61.5   59.5   
    Range   26.0-93.0   30.0-86.0   
Fracture, no. (%)    .96  
    Yes   11 (20.5)   12 (20.0)   
    No   43 (79.6)   48 (80.0)   
Hemoglobin, g/L    .53  
    Median   133   138   
    Range   (95-170)   (87-170)   
Serum monoclonal protein, no. (%)    .32  
    Positive   37 (68.5)   37 (59.7)   
    Negative   17 (31.5)   25 (40.3)   
Serum M spike, g/dL    .04  
    Median   1.0   0.3   
    Range   0.0-3.0   0.0-2.6   
Urine monoclonal protein, no. (%)    < .001  
    Positive   31 (60.8)   11 (20.4)   
    Negative   20 (39.2)   43 (79.6)   
Urine M spike, g/24 h    .58  
    Median   0.0   0.0   
    Range   0.0-0.2   0.0-0.2   
Reduction in uninvolved Igs, no. (%)    .19  
    0   15 (51.7)   21 (72.4)   
    1   10 (34.5)   7 (24.1)   
    2
 
1 (3.4)
 
4 (13.8)
 

 

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