Descriptive characteristics of non-Hodgkin lymphoma (NHL) cases and controls with genotype and diet information, the NCI-SEER Case-Control Study, 1998-2000
| Characteristic . | Among subjects with genotype data, no. (%)† . | Among subjects with both genotype and diet data, no. (%)† . | ||
|---|---|---|---|---|
| NHL cases . | Controls . | NHL cases . | Controls . | |
| No. of cases | 1141 | 949 | 386 | 319 |
| Men | 629 (55) | 506 (53) | 215 (56) | 166 (52) |
| Women | 512 (45) | 443 (47) | 171 (44) | 153 (48) |
| Age at enrollment | ||||
| Younger than 45 y | 203 (18) | 150 (16) | 67 (17) | 40 (13) |
| 45 y to younger than 55 y | 252 (22) | 178 (19) | 90 (23) | 54 (17) |
| 55 y to younger than 65 y | 311 (27) | 228 (24) | 105 (27) | 79 (25) |
| 65 y to 74 y | 375 (33)* | 393 (41) | 124 (32)* | 146 (46) |
| Race‡ | ||||
| White | 981 (86)* | 760 (80) | 366 (95) | 305 (96) |
| African American | 80 (7) | 127 (13) | 0 (0) | NA |
| Others | 80 (7) | 62 (7) | 20 (5) | 14 (4) |
| Study center | ||||
| Detroit | 236 (21) | 170 (18) | 38 (10) | 26 (8) |
| Iowa | 333 (29) | 272 (29) | 151 (39) | 118 (37) |
| Los Angeles | 283 (25) | 238 (25) | 87 (23) | 69 (22) |
| Seattle | 289 (25) | 269 (28) | 110 (29) | 106 (33) |
| Education | ||||
| Less than 12 y | 109 (10) | 89 (10) | 26 (7) | 28 (9) |
| 12 to less than 16 y | 693 (61) | 543 (58) | 237 (61) | 178 (56) |
| 16 y or more | 334 (29) | 297 (32) | 123 (32) | 113 (35) |
| Family history of NHL | 48 (4) | 30 (3) | 20 (5) | 16 (5) |
| Body mass index | ||||
| Normal, less than 25 kg/m2 | 459 (40) | 389 (41) | 142 (37) | 112 (35) |
| Overweight, 25 kg/m2 or greater to less than 30 kg/m2 | 408 (36) | 336 (35) | 160 (41) | 132 (41) |
| Obese, 30 kg/m2 or greater | 274 (24) | 224 (24) | 84 (22) | 75 (24) |
| DNA source | ||||
| Blood | 735 (64) | 631 (66) | 271 (70) | 242 (76) |
| Buccal tissue | 395 (35) | 313 (33) | 112 (29) | 75 (24) |
| Both | 11 (1) | 5 (1) | 3 (1) | 2 (1) |
| Patient pathology | ||||
| All B-cell | 927 (81) | NA | 327 (85) | NA |
| Diffuse large B-cell | 360 (32) | NA | 142 (37) | NA |
| Follicular | 271 (24) | NA | 98 (25) | NA |
| SLL | 147 (13) | NA | 48 (12) | NA |
| Marginal zone | 92 (8) | NA | 26 (7) | NA |
| Other | 57 (5) | NA | 13 (3) | NA |
| All T-cell | 73 (6) | NA | 21 (5) | NA |
| NOS | 141 (12) | NA | 38 (10) | NA |
| Characteristic . | Among subjects with genotype data, no. (%)† . | Among subjects with both genotype and diet data, no. (%)† . | ||
|---|---|---|---|---|
| NHL cases . | Controls . | NHL cases . | Controls . | |
| No. of cases | 1141 | 949 | 386 | 319 |
| Men | 629 (55) | 506 (53) | 215 (56) | 166 (52) |
| Women | 512 (45) | 443 (47) | 171 (44) | 153 (48) |
| Age at enrollment | ||||
| Younger than 45 y | 203 (18) | 150 (16) | 67 (17) | 40 (13) |
| 45 y to younger than 55 y | 252 (22) | 178 (19) | 90 (23) | 54 (17) |
| 55 y to younger than 65 y | 311 (27) | 228 (24) | 105 (27) | 79 (25) |
| 65 y to 74 y | 375 (33)* | 393 (41) | 124 (32)* | 146 (46) |
| Race‡ | ||||
| White | 981 (86)* | 760 (80) | 366 (95) | 305 (96) |
| African American | 80 (7) | 127 (13) | 0 (0) | NA |
| Others | 80 (7) | 62 (7) | 20 (5) | 14 (4) |
| Study center | ||||
| Detroit | 236 (21) | 170 (18) | 38 (10) | 26 (8) |
| Iowa | 333 (29) | 272 (29) | 151 (39) | 118 (37) |
| Los Angeles | 283 (25) | 238 (25) | 87 (23) | 69 (22) |
| Seattle | 289 (25) | 269 (28) | 110 (29) | 106 (33) |
| Education | ||||
| Less than 12 y | 109 (10) | 89 (10) | 26 (7) | 28 (9) |
| 12 to less than 16 y | 693 (61) | 543 (58) | 237 (61) | 178 (56) |
| 16 y or more | 334 (29) | 297 (32) | 123 (32) | 113 (35) |
| Family history of NHL | 48 (4) | 30 (3) | 20 (5) | 16 (5) |
| Body mass index | ||||
| Normal, less than 25 kg/m2 | 459 (40) | 389 (41) | 142 (37) | 112 (35) |
| Overweight, 25 kg/m2 or greater to less than 30 kg/m2 | 408 (36) | 336 (35) | 160 (41) | 132 (41) |
| Obese, 30 kg/m2 or greater | 274 (24) | 224 (24) | 84 (22) | 75 (24) |
| DNA source | ||||
| Blood | 735 (64) | 631 (66) | 271 (70) | 242 (76) |
| Buccal tissue | 395 (35) | 313 (33) | 112 (29) | 75 (24) |
| Both | 11 (1) | 5 (1) | 3 (1) | 2 (1) |
| Patient pathology | ||||
| All B-cell | 927 (81) | NA | 327 (85) | NA |
| Diffuse large B-cell | 360 (32) | NA | 142 (37) | NA |
| Follicular | 271 (24) | NA | 98 (25) | NA |
| SLL | 147 (13) | NA | 48 (12) | NA |
| Marginal zone | 92 (8) | NA | 26 (7) | NA |
| Other | 57 (5) | NA | 13 (3) | NA |
| All T-cell | 73 (6) | NA | 21 (5) | NA |
| NOS | 141 (12) | NA | 38 (10) | NA |
NA indicates not applicable.
P < .05 for comparison of cases versus controls, within the group of genetic and genetic + diet information availability, using Wilcoxon nonparametric test for continuous variables and using Pearson chi-squared test for categoric variables.
Number and percent for each category of descriptive characteristic variables.
By study design, study participants were divided into 2 groups for detailed questionnaires, and all African Americans and a random half of the rest were assigned to one group for information on self/family medical history, while the other participants were assigned to fill out diet information.