Most frequent (5% or more) nonhematologic adverse events associated with nilotinib
| Adverse event . | Patients, no. (%) . | |
|---|---|---|
| All grades . | Grade 3/4 . | |
| Rash | 79 (28) | 9 (3) |
| Nausea | 66 (24) | 3 (1) |
| Pruritus | 67 (24) | 3 (1) |
| Fatigue | 52 (19) | 3 (1) |
| Headache | 52 (19) | 5 (2) |
| Constipation | 34 (12) | 0 |
| Diarrhea | 32 (11) | 6 (2) |
| Vomiting | 30 (11) | 2 (< 1) |
| Myalgia | 23 (8) | 3 (1) |
| Extremity pain | 13 (5) | 2 (< 1) |
| Adverse event . | Patients, no. (%) . | |
|---|---|---|
| All grades . | Grade 3/4 . | |
| Rash | 79 (28) | 9 (3) |
| Nausea | 66 (24) | 3 (1) |
| Pruritus | 67 (24) | 3 (1) |
| Fatigue | 52 (19) | 3 (1) |
| Headache | 52 (19) | 5 (2) |
| Constipation | 34 (12) | 0 |
| Diarrhea | 32 (11) | 6 (2) |
| Vomiting | 30 (11) | 2 (< 1) |
| Myalgia | 23 (8) | 3 (1) |
| Extremity pain | 13 (5) | 2 (< 1) |