Table 1

List of the 10 most differentially expressed genes in LPS-stimulated adult (Ad) versus neonatal (NB) moDCs

Gene descriptionSymbolAd
NB
Ad LPS vs NB LPS, fold
Basal*LPS*Basal*LPS*
Chemokine (C-X-C motif) ligand 9 CXCL9 27 ± 1 1982 ± 997 29 ± 3 50 ± 11 39.6 
Chemokine (C-X-C motif) ligand 11 CXCL11 13 ± 1 2213 ± 192 13 ± 1 88 ± 57 25.1 
Tumor necrosis factor (ligand) superfamily, member 10 TNFSF10 40 ± 13 1140 ± 359 24 ± 5 166 ± 83 6.9 
Claudin 1 CLDN1 16 ± 1 108 ± 59 15 ± 1 18 ± 3 5.9 
Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A APOBEC3A 27 ± 3 1351 ± 41 23 ± 2 231 ± 161 5.8 
Exostoses (multiple) 1 EXT1 54 ± 3 468 ± 137 44 ± 5 82 ± 20 5.7 
Zinc finger CCCH type, antiviral 1 ZAP 54 ± 3 628 ± 79 35 ± 2 116 ± 38 5.4 
Neutrophil cytosolic factor 1 (47kDa) NCF1 500 ± 219 2927 ± 629 148 ± 51 567 ± 115 5.2 
Homeo box (expressed in ES cells) 1 HESX1 27 ± 5 334 ± 95 27 ± 2 65 ± 26 5.1 
CD38 antigen (p45) CD38 89 ± 8 1674 ± 242 74 ± 8 362 ± 145 4.6 
Sialoadhesin SN 95 ± 7 562 ± 194 70 ± 11 125 ± 33 4.5 
Gene descriptionSymbolAd
NB
Ad LPS vs NB LPS, fold
Basal*LPS*Basal*LPS*
Chemokine (C-X-C motif) ligand 9 CXCL9 27 ± 1 1982 ± 997 29 ± 3 50 ± 11 39.6 
Chemokine (C-X-C motif) ligand 11 CXCL11 13 ± 1 2213 ± 192 13 ± 1 88 ± 57 25.1 
Tumor necrosis factor (ligand) superfamily, member 10 TNFSF10 40 ± 13 1140 ± 359 24 ± 5 166 ± 83 6.9 
Claudin 1 CLDN1 16 ± 1 108 ± 59 15 ± 1 18 ± 3 5.9 
Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A APOBEC3A 27 ± 3 1351 ± 41 23 ± 2 231 ± 161 5.8 
Exostoses (multiple) 1 EXT1 54 ± 3 468 ± 137 44 ± 5 82 ± 20 5.7 
Zinc finger CCCH type, antiviral 1 ZAP 54 ± 3 628 ± 79 35 ± 2 116 ± 38 5.4 
Neutrophil cytosolic factor 1 (47kDa) NCF1 500 ± 219 2927 ± 629 148 ± 51 567 ± 115 5.2 
Homeo box (expressed in ES cells) 1 HESX1 27 ± 5 334 ± 95 27 ± 2 65 ± 26 5.1 
CD38 antigen (p45) CD38 89 ± 8 1674 ± 242 74 ± 8 362 ± 145 4.6 
Sialoadhesin SN 95 ± 7 562 ± 194 70 ± 11 125 ± 33 4.5 
*

Gene expression is described as mean intensity ± SEM obtained from 3 donors in each group.

IFN-dependent genes.

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