Adverse events
| Classification . | No. of patients . | No. of episodes . | Severity, grade* . | No. of related episodes† . | No. of unrelated episodes . |
|---|---|---|---|---|---|
| Serious | 11 | 22 | 2-5 | 0 | 22 |
| Nonserious‡ | 75 | 100 | 1-3 | 53 | 47 |
| Emesis | 12 | 19 | 1-2 | 11 | 8 |
| Nausea | 10 | 18 | 1-2 | 17 | 1 |
| Increased AST/ALT level | 10 | 10 | 1-3 | 6 | 4 |
| Anemia | 8 | 9 | 1-3 | 5 | 4 |
| Edema | 4 | 7 | 1-3 | 7 | 0 |
| Diarrhea | 5 | 5 | 1-3 | 2 | 3 |
| Thrombocytopenia | 2 | 3 | 2-3 | 2 | 1 |
| Neutropenia | 2 | 2 | 2-3 | 2 | 0 |
| Anorexia | 1 | 1 | 2 | 1 | 0 |
| Classification . | No. of patients . | No. of episodes . | Severity, grade* . | No. of related episodes† . | No. of unrelated episodes . |
|---|---|---|---|---|---|
| Serious | 11 | 22 | 2-5 | 0 | 22 |
| Nonserious‡ | 75 | 100 | 1-3 | 53 | 47 |
| Emesis | 12 | 19 | 1-2 | 11 | 8 |
| Nausea | 10 | 18 | 1-2 | 17 | 1 |
| Increased AST/ALT level | 10 | 10 | 1-3 | 6 | 4 |
| Anemia | 8 | 9 | 1-3 | 5 | 4 |
| Edema | 4 | 7 | 1-3 | 7 | 0 |
| Diarrhea | 5 | 5 | 1-3 | 2 | 3 |
| Thrombocytopenia | 2 | 3 | 2-3 | 2 | 1 |
| Neutropenia | 2 | 2 | 2-3 | 2 | 0 |
| Anorexia | 1 | 1 | 2 | 1 | 0 |
Common Toxicity Criteria (CTC) version 3.0.
Related events include possibly, probably, or definitely related events and unrelated events include those unlikely to be or definitely not related.
Shown are those categories of nonserious adverse events that included at least one episode with probable or possible relationship to imatinib therapy.