Dose intensity and total dose of cyclophosphamide and doxorubicin as planned and actual doses administered in CHOP-21 and I-CHOP
| Regimen . | Dose intensity, median mg/m2/wk (range) . | Total dose, mg/m2 (range) . | ||
|---|---|---|---|---|
| Cyclophosphamide . | Doxorubicin . | Cyclophosphamide . | Doxorubicin . | |
| Planned | ||||
| CHOP-21 | 250 | 17 | 6000 | 400 |
| I-CHOP | 500 | 35 | 6000 | 420 |
| Administered | ||||
| CHOP-21 | 243 (139-267) | 16.2 (9.3-17.8) | 5966 (417-6461) | 398 (28-428) |
| I-CHOP | 463 (155-532) | 32.3 (10.4-37.4) | 5984 (1000-7544) | 415 (71-561) |
| Regimen . | Dose intensity, median mg/m2/wk (range) . | Total dose, mg/m2 (range) . | ||
|---|---|---|---|---|
| Cyclophosphamide . | Doxorubicin . | Cyclophosphamide . | Doxorubicin . | |
| Planned | ||||
| CHOP-21 | 250 | 17 | 6000 | 400 |
| I-CHOP | 500 | 35 | 6000 | 420 |
| Administered | ||||
| CHOP-21 | 243 (139-267) | 16.2 (9.3-17.8) | 5966 (417-6461) | 398 (28-428) |
| I-CHOP | 463 (155-532) | 32.3 (10.4-37.4) | 5984 (1000-7544) | 415 (71-561) |