Table 7 Cumulative incidence of... | American Society of Hematology

Table 7

Cumulative incidence of nonrelapse mortality at 2 y according to grade of acute GVHD, type of donor, and hyperacute GVHD

Group	Total no. of patients	Acute GVHD grade II					Acute GVHD grades III-IV
Group	Total no. of patients	No. of patients (%)	% CI NRM	HR	95% CI	P	No. of patients (%)	% CI NRM	HR	95% CI	P
Mrel and no hyperacute	109	61 (56)	31	1.0	Reference	—	48 (44)	58	1.0	Reference	—
Mrel and hyperacute	28	19 (68)	26	0.6	0.2-1.6	.3	9 (32)	33	0.8	0.25-2.7	.8
MUD/MMrel and no hyperacute	82	46 (56)	35	1.1	0.6-2.1	.8	36 (44)	64	1.5	0.9-2.6	.12
MUD/MMrel and hyperacute	45	25 (56)	54	1.5*	0.8-3.0	.2	20 (44)	80	2.5†	1.4-4.6	.003
Overall	264	151 (57)	35	—	—	—	113 (43)	62	2.8‡	1.9-3.9‡	< .001‡

Group	Total no. of patients	Acute GVHD grade II					Acute GVHD grades III-IV
Group	Total no. of patients	No. of patients (%)	% CI NRM	HR	95% CI	P	No. of patients (%)	% CI NRM	HR	95% CI	P
Mrel and no hyperacute	109	61 (56)	31	1.0	Reference	—	48 (44)	58	1.0	Reference	—
Mrel and hyperacute	28	19 (68)	26	0.6	0.2-1.6	.3	9 (32)	33	0.8	0.25-2.7	.8
MUD/MMrel and no hyperacute	82	46 (56)	35	1.1	0.6-2.1	.8	36 (44)	64	1.5	0.9-2.6	.12
MUD/MMrel and hyperacute	45	25 (56)	54	1.5*	0.8-3.0	.2	20 (44)	80	2.5†	1.4-4.6	.003
Overall	264	151 (57)	35	—	—	—	113 (43)	62	2.8‡	1.9-3.9‡	< .001‡

% CI indicates percent cumulative incidence; NRM, nonrelapse mortality; —, not applicable.

Comparing MUD/MMrel and hyperacute to all other subgroups, HR (95% CI) is 1.6 (0.9-2.9) (P = .1).

Comparing MUD/MMrel and hyperacute to all other subgroups, HR (95% CI) is 2.2 (1.2-3.8) (P = .001).

Comparing NRM for overall grade II versus grades III-IV.