Table 3 Number of patients with toxicity... | American Society of Hematology

Table 3

Number of patients with toxicity following pegaspargase administration (n = 25)

Adverse effect	Toxicity grade, no. of patients			Total no. of patients
Adverse effect	Grades 1, 2	Grade 3	Grade 4	Total no. of patients
Hyperbilirubinemia	16	1	1	18
Elevated AST/ALT level	16	2	1	19
Hyperglycemia	15	2	2	19
Nausea/vomiting	9	1	0	10
Diarrhea	4	0	0	4
Constipation	6	0	0	6
Fever	2	0	0	2
Neuropathy	5	0	0	5
Fatigue	2	0	0	2
Deep vein thrombosis	0	1	0	1

Adverse effect	Toxicity grade, no. of patients			Total no. of patients
Adverse effect	Grades 1, 2	Grade 3	Grade 4	Total no. of patients
Hyperbilirubinemia	16	1	1	18
Elevated AST/ALT level	16	2	1	19
Hyperglycemia	15	2	2	19
Nausea/vomiting	9	1	0	10
Diarrhea	4	0	0	4
Constipation	6	0	0	6
Fever	2	0	0	2
Neuropathy	5	0	0	5
Fatigue	2	0	0	2
Deep vein thrombosis	0	1	0	1

There were no allergic reactions or pancreatitis.