Percentages of activated CD4+ T cells in tissues of normal macaques (aged 3–50 days)
| . | 503-99 . | GB14 . | GB15 . | 416-99 . | 395-99 . | GA98 . | 191-99 . | EC73 . | DP44 . | 257-99 . | GA24 . | Mean . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Blood | ||||||||||||
| CD69+ | 0.6 | 0.5 | 0.1 | 0.7 | NA | 0.1 | 1.8 | 0.2 | 0.4 | 0.8 | 0.4 | 0.6 |
| CD25+ | 6.1 | 5.5 | 3.6 | 8.7 | NA | 4.9 | 5.7 | 3.4 | 6.8 | 8.0 | 6.3 | 5.9 |
| CD25+CD69+ | 0.1 | 0.1 | 0.1 | 0.2 | NA | 0.1 | 0.6 | 0.0 | 0.1 | 0.1 | 0.1 | 0.1 |
| Axillary LN | ||||||||||||
| CD69+ | 11.7 | 12.0 | NA | 16.1 | 22.4 | 12.4 | 18.0 | 9.8 | 17.9 | 19.9 | 19.9 | 14.8 |
| CD25+ | 6.1 | 6.7 | NA | 9.8 | 5.9 | 9.4 | 7.1 | 2.2 | 9.9 | 6.7 | 8.1 | 6.6 |
| CD25+CD69+ | 1.4 | 1.7 | NA | 4.1 | 2.4 | 2.0 | 2.9 | 0.7 | 3.5 | 3.2 | 3.5 | 2.3 |
| Spleen | ||||||||||||
| CD69+ | 12.8 | 15.0 | 12.5 | 8.7 | 13.6 | 10.9 | 11.6 | 12.0 | 17.2 | NA | 23.9 | 12.8 |
| CD25+ | 5.5 | 17.4 | 3.7 | 12.1 | 6.1 | 9.9 | 8.9 | 7.3 | 12.1 | NA | 13.4 | 9.5 |
| CD25+CD69+ | 1.7 | 5.9 | 1.3 | 3.3 | 1.9 | 2.9 | 2.6 | 2.2 | 3.2 | NA | 6.3 | 3.0 |
| Jejunum LPL | ||||||||||||
| CD69+ | 21.9 | 43.6 | 70.4 | 37.7 | 93.1 | 72.5 | 95.8 | 93.2 | 95.1 | 93.5 | 68.9 | 71.4 |
| CD25+ | 12.2 | 28.9 | 49.3 | 28.7 | 40.2 | 35.9 | 30.6 | 34.2 | 40.6 | 25.9 | 43.5 | 33.6 |
| CD25+CD69+ | 8.1 | 24.5 | 44.7 | 24.6 | 30.6 | 33.9 | 30.1 | 33.6 | 39.7 | 25.2 | 39.6 | 30.4 |
| . | 503-99 . | GB14 . | GB15 . | 416-99 . | 395-99 . | GA98 . | 191-99 . | EC73 . | DP44 . | 257-99 . | GA24 . | Mean . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Blood | ||||||||||||
| CD69+ | 0.6 | 0.5 | 0.1 | 0.7 | NA | 0.1 | 1.8 | 0.2 | 0.4 | 0.8 | 0.4 | 0.6 |
| CD25+ | 6.1 | 5.5 | 3.6 | 8.7 | NA | 4.9 | 5.7 | 3.4 | 6.8 | 8.0 | 6.3 | 5.9 |
| CD25+CD69+ | 0.1 | 0.1 | 0.1 | 0.2 | NA | 0.1 | 0.6 | 0.0 | 0.1 | 0.1 | 0.1 | 0.1 |
| Axillary LN | ||||||||||||
| CD69+ | 11.7 | 12.0 | NA | 16.1 | 22.4 | 12.4 | 18.0 | 9.8 | 17.9 | 19.9 | 19.9 | 14.8 |
| CD25+ | 6.1 | 6.7 | NA | 9.8 | 5.9 | 9.4 | 7.1 | 2.2 | 9.9 | 6.7 | 8.1 | 6.6 |
| CD25+CD69+ | 1.4 | 1.7 | NA | 4.1 | 2.4 | 2.0 | 2.9 | 0.7 | 3.5 | 3.2 | 3.5 | 2.3 |
| Spleen | ||||||||||||
| CD69+ | 12.8 | 15.0 | 12.5 | 8.7 | 13.6 | 10.9 | 11.6 | 12.0 | 17.2 | NA | 23.9 | 12.8 |
| CD25+ | 5.5 | 17.4 | 3.7 | 12.1 | 6.1 | 9.9 | 8.9 | 7.3 | 12.1 | NA | 13.4 | 9.5 |
| CD25+CD69+ | 1.7 | 5.9 | 1.3 | 3.3 | 1.9 | 2.9 | 2.6 | 2.2 | 3.2 | NA | 6.3 | 3.0 |
| Jejunum LPL | ||||||||||||
| CD69+ | 21.9 | 43.6 | 70.4 | 37.7 | 93.1 | 72.5 | 95.8 | 93.2 | 95.1 | 93.5 | 68.9 | 71.4 |
| CD25+ | 12.2 | 28.9 | 49.3 | 28.7 | 40.2 | 35.9 | 30.6 | 34.2 | 40.6 | 25.9 | 43.5 | 33.6 |
| CD25+CD69+ | 8.1 | 24.5 | 44.7 | 24.6 | 30.6 | 33.9 | 30.1 | 33.6 | 39.7 | 25.2 | 39.6 | 30.4 |
Data indicate percentages of gated CD4+ T cells expressing CD25 and/or CD69. See Table 1 for more detail on macaques.
LN indicates lymph node; LPL, lamina propria lymphocyte; and NA, not available.