Table 2

Genes down-regulated by GC treatment

Gene symbolDescription (NCBI Gene)N-foldP
T-cell chemotaxis    
    CXCL11* Chemokine (C-X-C motif) ligand 11 −4.9 .017 
    CXCL10* Chemokine (C-X-C motif) ligand 10 −3.3 .017 
    CCL5 Chemokine (C-C motif) ligand 5 −2.5 .016 
    CXCL9* Chemokine (C-X-C motif) ligand 9 −2.0 .030 
Adhesion    
    FCN1 Ficolin (collagen/fibrinogen domain containing) 1 −2.5 .021 
    ITGAL Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) −2.5 .029 
    CD36 CD36 antigen (collagen type I receptor, thrombospondin receptor) −2.2 .017 
    LST1* Leukocyte specific transcript 1 −2.0 .009 
    OLR1 Oxidized low density lipoprotein (lectin-like) receptor 1 −2.0 .017 
Apoptosis    
    STAT1* Signal transducer and activator of transcription 1, 91 kDa −3.4 .023 
    DNASE1L3 Deoxyribonuclease I-like 3 −2.6 .019 
    TNFSF10 Tumor necrosis factor (ligand) superfamily, member 10 −2.2 .038 
    PEA15 Phosphoprotein enriched in astrocytes 15 (antiapoptosis) −2.1 .005 
    CST7 Cystatin F (leukocystatin) −2.1 .029 
Oxidative functions    
    PTGS1 Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) −2.9 .006 
    SCO2 SCO cytochrome oxidase deficient homolog 2 (yeast) −2.4 .018 
    CYBB Cytochrome b-245, beta polypeptide (chronic granulomatous disease), component NAPDH oxidase −2.0 .023 
Genes up-regulated by IFNγ    
    GBP1* Guanylate binding protein 1, interferon-inducible, 67 kDa −2.6 .012 
    IFITM1* Interferon induced transmembrane protein 1 (9–27) −2.1 .040 
    WARS* Tryptophanyl-tRNA synthetase −2.1 .017 
Gene symbolDescription (NCBI Gene)N-foldP
T-cell chemotaxis    
    CXCL11* Chemokine (C-X-C motif) ligand 11 −4.9 .017 
    CXCL10* Chemokine (C-X-C motif) ligand 10 −3.3 .017 
    CCL5 Chemokine (C-C motif) ligand 5 −2.5 .016 
    CXCL9* Chemokine (C-X-C motif) ligand 9 −2.0 .030 
Adhesion    
    FCN1 Ficolin (collagen/fibrinogen domain containing) 1 −2.5 .021 
    ITGAL Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) −2.5 .029 
    CD36 CD36 antigen (collagen type I receptor, thrombospondin receptor) −2.2 .017 
    LST1* Leukocyte specific transcript 1 −2.0 .009 
    OLR1 Oxidized low density lipoprotein (lectin-like) receptor 1 −2.0 .017 
Apoptosis    
    STAT1* Signal transducer and activator of transcription 1, 91 kDa −3.4 .023 
    DNASE1L3 Deoxyribonuclease I-like 3 −2.6 .019 
    TNFSF10 Tumor necrosis factor (ligand) superfamily, member 10 −2.2 .038 
    PEA15 Phosphoprotein enriched in astrocytes 15 (antiapoptosis) −2.1 .005 
    CST7 Cystatin F (leukocystatin) −2.1 .029 
Oxidative functions    
    PTGS1 Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) −2.9 .006 
    SCO2 SCO cytochrome oxidase deficient homolog 2 (yeast) −2.4 .018 
    CYBB Cytochrome b-245, beta polypeptide (chronic granulomatous disease), component NAPDH oxidase −2.0 .023 
Genes up-regulated by IFNγ    
    GBP1* Guanylate binding protein 1, interferon-inducible, 67 kDa −2.6 .012 
    IFITM1* Interferon induced transmembrane protein 1 (9–27) −2.1 .040 
    WARS* Tryptophanyl-tRNA synthetase −2.1 .017 
*

Genes up-regulated by IFNγ.

Facultative value, the signal in GC-treated cells was below the detection limit (detection P < .05, Affymetrix MAS 5.1).

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