Genes up-regulated by GC treatment
| Gene symbol . | Description (NCBI gene) . | N-fold . | P . |
|---|---|---|---|
| Antioxidative | |||
| SLC1A3 | Solute carrier family 1 (glial high-affinity glutamate transporter), member 3 | 6.8† | <.001 |
| SESN1* | Sestrin 1 | 4.9 | .002 |
| ADORA3* | Adenosine A3 receptor | 4.3 | .009 |
| GCLC | Glutamate-cysteine ligase, catalytic subunit | 2.6 | .012 |
| GLO1 | Glyoxalase I | 2.3 | .026 |
| AKR1B1* | Aldo-keto reductase family 1, member B1 (aldose reductase) | 2.3 | .026 |
| Migration/chemotaxis | |||
| FPR1 | Formyl peptide receptor 1 | 3.0 | .004 |
| KIAA0551 | Traf2 and NCK interacting kinase | 2.9 | .024 |
| AQP9 | Aquaporin-9 | 2.5† | .012 |
| MTSS1 | Metastasis suppressor 1 | 2.4 | <.001 |
| Phagocytosis | |||
| MERTK | c-mer proto-oncogene tyrosine kinase | 4.9 | .004 |
| FLJ10462 | Hypothetical protein FLJ10462 (WIPI49) | 4.5† | .003 |
| MFGE8 | Milk fat globule-EGF factor 8 protein | 4.0† | .008 |
| C1QA | Complement component 1, q subcomponent, alpha polypeptide | 2.5 | .012 |
| MRC1 | Mannose receptor, C type 1 | 2.4 | .027 |
| FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 2.3 | .039 |
| Genes with known anti-inflammatory functions | |||
| CD1D* | CD1D antigen, d polypeptide | 2.7 | .001 |
| LILRB1* | Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 2.3 | .046 |
| IL1R2* | Interleukin 1 receptor, type II | 28.4† | .009 |
| CD163* | CD163 antigen | 4.5 | .001 |
| DSIPI* | Delta sleep inducing peptide, immunoreactor | 4.1† | .009 |
| FCAR* | Fc fragment of IgA, receptor for | 3.4† | .012 |
| IL10* | Interleukin 10 | 2.3 | .019 |
| Gene symbol . | Description (NCBI gene) . | N-fold . | P . |
|---|---|---|---|
| Antioxidative | |||
| SLC1A3 | Solute carrier family 1 (glial high-affinity glutamate transporter), member 3 | 6.8† | <.001 |
| SESN1* | Sestrin 1 | 4.9 | .002 |
| ADORA3* | Adenosine A3 receptor | 4.3 | .009 |
| GCLC | Glutamate-cysteine ligase, catalytic subunit | 2.6 | .012 |
| GLO1 | Glyoxalase I | 2.3 | .026 |
| AKR1B1* | Aldo-keto reductase family 1, member B1 (aldose reductase) | 2.3 | .026 |
| Migration/chemotaxis | |||
| FPR1 | Formyl peptide receptor 1 | 3.0 | .004 |
| KIAA0551 | Traf2 and NCK interacting kinase | 2.9 | .024 |
| AQP9 | Aquaporin-9 | 2.5† | .012 |
| MTSS1 | Metastasis suppressor 1 | 2.4 | <.001 |
| Phagocytosis | |||
| MERTK | c-mer proto-oncogene tyrosine kinase | 4.9 | .004 |
| FLJ10462 | Hypothetical protein FLJ10462 (WIPI49) | 4.5† | .003 |
| MFGE8 | Milk fat globule-EGF factor 8 protein | 4.0† | .008 |
| C1QA | Complement component 1, q subcomponent, alpha polypeptide | 2.5 | .012 |
| MRC1 | Mannose receptor, C type 1 | 2.4 | .027 |
| FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 2.3 | .039 |
| Genes with known anti-inflammatory functions | |||
| CD1D* | CD1D antigen, d polypeptide | 2.7 | .001 |
| LILRB1* | Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 2.3 | .046 |
| IL1R2* | Interleukin 1 receptor, type II | 28.4† | .009 |
| CD163* | CD163 antigen | 4.5 | .001 |
| DSIPI* | Delta sleep inducing peptide, immunoreactor | 4.1† | .009 |
| FCAR* | Fc fragment of IgA, receptor for | 3.4† | .012 |
| IL10* | Interleukin 10 | 2.3 | .019 |