G-CSF and hematologic recovery
| . | Intent-to-treat . | Treated-as-assigned . | ||||
|---|---|---|---|---|---|---|
| No G-CSF . | G-CSF . | P . | No G-CSF . | G-CSF . | P . | |
| AIE, median d | ||||||
| Total | ||||||
| Neutropenia | 23.0* | 18.0* | .01* | 22.0 | 18.0 | .11 |
| Thrombocytopenia | 6.0 | 6.0 | .97 | 4.5 | 7.0 | .46 |
| SR | ||||||
| Neutropenia | 22.0 | 18.0 | .21 | 20.5 | 18.5 | .49 |
| Thrombocytopenia | 9.0 | 7.5 | .81 | 8.0 | 8.0 | .83 |
| HR | ||||||
| Neutropenia | 24.0* | 18.0* | .03* | 22.5 | 18.0 | .12 |
| Thrombocytopenia | 6.0 | 8.0 | .28 | 5.0 | 8.5 | .13 |
| Down syndrome, median d | ||||||
| Neutropenia | 22.5 | 19.0 | .37 | 23.0 | 21.0 | .54 |
| Thrombocytopenia | 2.0 | 1.0 | .15 | 2.0 | 1.0 | .15 |
| HAM, median d | ||||||
| Total | ||||||
| Neutropenia | 16.0* | 11.0* | .001* | 16.0* | 11.0* | .002* |
| Thrombocytopenia | 4.0 | 5.0 | .79 | 3.0 | 4.0 | .69 |
| SR | ||||||
| Neutropenia | 17.0* | 11.0* | .02* | 17.5 | 12.0 | .07 |
| Thrombocytopenia | 5.0 | 5.0 | .98 | 4.5 | 5.0 | .78 |
| HR | ||||||
| Neutropenia | 15.5* | 11.0* | .008* | 15.0* | 10.0* | .007* |
| Thrombocytopenia | 2.0 | 4.5 | .79 | 2.0 | 3.0 | .97 |
| . | Intent-to-treat . | Treated-as-assigned . | ||||
|---|---|---|---|---|---|---|
| No G-CSF . | G-CSF . | P . | No G-CSF . | G-CSF . | P . | |
| AIE, median d | ||||||
| Total | ||||||
| Neutropenia | 23.0* | 18.0* | .01* | 22.0 | 18.0 | .11 |
| Thrombocytopenia | 6.0 | 6.0 | .97 | 4.5 | 7.0 | .46 |
| SR | ||||||
| Neutropenia | 22.0 | 18.0 | .21 | 20.5 | 18.5 | .49 |
| Thrombocytopenia | 9.0 | 7.5 | .81 | 8.0 | 8.0 | .83 |
| HR | ||||||
| Neutropenia | 24.0* | 18.0* | .03* | 22.5 | 18.0 | .12 |
| Thrombocytopenia | 6.0 | 8.0 | .28 | 5.0 | 8.5 | .13 |
| Down syndrome, median d | ||||||
| Neutropenia | 22.5 | 19.0 | .37 | 23.0 | 21.0 | .54 |
| Thrombocytopenia | 2.0 | 1.0 | .15 | 2.0 | 1.0 | .15 |
| HAM, median d | ||||||
| Total | ||||||
| Neutropenia | 16.0* | 11.0* | .001* | 16.0* | 11.0* | .002* |
| Thrombocytopenia | 4.0 | 5.0 | .79 | 3.0 | 4.0 | .69 |
| SR | ||||||
| Neutropenia | 17.0* | 11.0* | .02* | 17.5 | 12.0 | .07 |
| Thrombocytopenia | 5.0 | 5.0 | .98 | 4.5 | 5.0 | .78 |
| HR | ||||||
| Neutropenia | 15.5* | 11.0* | .008* | 15.0* | 10.0* | .007* |
| Thrombocytopenia | 2.0 | 4.5 | .79 | 2.0 | 3.0 | .97 |
Significant differences.