Overall results (POG 1986 to 1999 and CCG 1988 to 1995)
| Group and NCI risk group . | No. patients . | 5-EFS (SE) . | 8-y EFS (SE) . | |||
|---|---|---|---|---|---|---|
| POG . | CCG* . | POG . | CCG . | POG . | CCG . | |
| All eligible† | ||||||
| Any | 6793§ | 3056 | 73.6 (0.7) | 75.9 (0.8) | 70.9 (0.9) | 72.7 (1.1) |
| Standard | 4740 | 2019 | 79.1 (0.7) | 80.2 (0.9) | 77.0 (1.0) | 78.3 (1.3) |
| High | 2040 | 1037 | 60.9 (1.4) | 67.5 (1.5) | 56.5 (1.9) | 64.9 (2.2) |
| All eligible with evaluable cytogenetics‡ | ||||||
| Any | 5056‖ | 1182 | 73.0 (0.8) | 76.0 (1.3) | 70.3 (1.1) | 74.2 (1.6) |
| Standard | 3516 | 776 | 78.7 (0.8) | 79.6 (1.5) | 76.6 (1.2) | 78.2 (2.1) |
| High | 1529 | 406 | 59.9 (1.6) | 69.1 (2.4) | 55.5 (2.3) | 66.5 (3.5) |
| Group and NCI risk group . | No. patients . | 5-EFS (SE) . | 8-y EFS (SE) . | |||
|---|---|---|---|---|---|---|
| POG . | CCG* . | POG . | CCG . | POG . | CCG . | |
| All eligible† | ||||||
| Any | 6793§ | 3056 | 73.6 (0.7) | 75.9 (0.8) | 70.9 (0.9) | 72.7 (1.1) |
| Standard | 4740 | 2019 | 79.1 (0.7) | 80.2 (0.9) | 77.0 (1.0) | 78.3 (1.3) |
| High | 2040 | 1037 | 60.9 (1.4) | 67.5 (1.5) | 56.5 (1.9) | 64.9 (2.2) |
| All eligible with evaluable cytogenetics‡ | ||||||
| Any | 5056‖ | 1182 | 73.0 (0.8) | 76.0 (1.3) | 70.3 (1.1) | 74.2 (1.6) |
| Standard | 3516 | 776 | 78.7 (0.8) | 79.6 (1.5) | 76.6 (1.2) | 78.2 (2.1) |
| High | 1529 | 406 | 59.9 (1.6) | 69.1 (2.4) | 55.5 (2.3) | 66.5 (3.5) |
The analyses of the CCG data do not include the patients from CCG 1952 and 1961, because they were included only in a limited analysis for TEL/AML1.
Includes all patients that had evaluable immunophenotyping and both those with and without evaluable cytogenetics.
Includes all patients who were eligible and had cytogenetic data.
Thirteen POG patients could not be classified into an NCI risk group due to missing WBC count at diagnosis and hence were only included in the overall (“Any”) analyses.
Eleven of the 5056 POG patients with evaluable cytogenetics could not be classified into an NCI risk group due to missing WBC count at diagnosis and hence were included only in the overall (“Any”) analyses.