Table 2 Similarity between human... | American Society of Hematology

Table 2

Similarity between human Menetrier disease and gastric histomorphologic alterations in CCR7^−/− mice

	CCR7^−/− mice	Menetrier disease
Gastric wall thickening	+	+
Foveolar hyperplasia	+	+
Cyst formation	+	+
Lymphoid follicles	+	(+)*
Superficial edema	(+)†	+
Gastritis cystica profunda (glands extending in submucosa)	+	+

	CCR7^−/− mice	Menetrier disease
Gastric wall thickening	+	+
Foveolar hyperplasia	+	+
Cyst formation	+	+
Lymphoid follicles	+	(+)*
Superficial edema	(+)†	+
Gastritis cystica profunda (glands extending in submucosa)	+	+

Variable degree of inflammation present with occasional lymphoid aggregates.

Variable degree of superficial edema present.