Multiple-variable model comparing patients to siblings by body mass index, sex, race/ethnicity, age at transplantation (or sibling's transplantation), and age at interview
. | Diabetes . | Hypertension . | Arterial disease . | MI . | CVA . | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | OR . | 95% CI . | P . | OR . | 95% CI . | P . | OR . | 95% CI . | P . | OR . | 95% CI . | P . | OR . | 95% CI . | P . |
Case status | |||||||||||||||
Allogeneic | 3.65 | 1.82-7.32 | < .001 | 2.06 | 1.39-3.04 | < .001 | 1.16 | 0.33-4.02 | .82 | 1.21 | 0.24-6.04 | .82 | 3.48 | 0.40-30.61 | .26 |
Autologous | 2.03 | 0.98-4.21 | .06 | 0.96 | 0.65-1.44 | .86 | 0.42 | 0.12-1.48 | .18 | 0.92 | 0.20-4.10 | .91 | 2.62 | 0.26-26.76 | .42 |
Sibling | Ref | Ref | Ref | Ref | Ref | ||||||||||
Sex | |||||||||||||||
Female | 0.80 | 0.51-1.25 | .33 | 0.88 | 0.65-1.17 | .37 | 0.11 | 0.02-0.49 | .004 | 0.55 | 0.16-1.91 | .35 | 1.32 | 0.34-5.09 | .30 |
Male | Ref | Ref | Ref | Ref | Ref | ||||||||||
Race/ethnicity | |||||||||||||||
Hispanic | 1.99 | 1.12-3.55 | .02 | 0.62 | 0.37-1.03 | .06 | NE | NE | NE | ||||||
Other | 2.18 | 0.99-4.79 | .06 | 0.83 | 0.44-1.57 | .57 | NE | NE | NE | ||||||
White | Ref | Ref | Ref | Ref | Ref | ||||||||||
Age at transplantation, y | 0.92 | 0.88-0.96 | < .001 | 0.98 | 0.96-1.01 | .25 | 0.91 | 0.83-0.99 | .03 | 0.95 | 0.85-1.06 | .37 | 0.96 | 0.85-1.08 | .50 |
Age at interview, y | 1.14 | 1.08-1.19 | < .001 | 1.07 | 1.04-1.11 | < .001 | 1.26 | 1.29-1.41 | < .001 | 1.16 | 1.01-1.32 | .04 | 1.06 | 0.93-1.20 | .38 |
BMI | 1.13 | 1.09-1.18 | < .001 | 1.07 | 1.04-1.10 | < .001 | 0.98 | 0.87-1.09 | .66 | 0.99 | 0.87-1.12 | .83 | 0.92 | 0.79-1.08 | .32 |
. | Diabetes . | Hypertension . | Arterial disease . | MI . | CVA . | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | OR . | 95% CI . | P . | OR . | 95% CI . | P . | OR . | 95% CI . | P . | OR . | 95% CI . | P . | OR . | 95% CI . | P . |
Case status | |||||||||||||||
Allogeneic | 3.65 | 1.82-7.32 | < .001 | 2.06 | 1.39-3.04 | < .001 | 1.16 | 0.33-4.02 | .82 | 1.21 | 0.24-6.04 | .82 | 3.48 | 0.40-30.61 | .26 |
Autologous | 2.03 | 0.98-4.21 | .06 | 0.96 | 0.65-1.44 | .86 | 0.42 | 0.12-1.48 | .18 | 0.92 | 0.20-4.10 | .91 | 2.62 | 0.26-26.76 | .42 |
Sibling | Ref | Ref | Ref | Ref | Ref | ||||||||||
Sex | |||||||||||||||
Female | 0.80 | 0.51-1.25 | .33 | 0.88 | 0.65-1.17 | .37 | 0.11 | 0.02-0.49 | .004 | 0.55 | 0.16-1.91 | .35 | 1.32 | 0.34-5.09 | .30 |
Male | Ref | Ref | Ref | Ref | Ref | ||||||||||
Race/ethnicity | |||||||||||||||
Hispanic | 1.99 | 1.12-3.55 | .02 | 0.62 | 0.37-1.03 | .06 | NE | NE | NE | ||||||
Other | 2.18 | 0.99-4.79 | .06 | 0.83 | 0.44-1.57 | .57 | NE | NE | NE | ||||||
White | Ref | Ref | Ref | Ref | Ref | ||||||||||
Age at transplantation, y | 0.92 | 0.88-0.96 | < .001 | 0.98 | 0.96-1.01 | .25 | 0.91 | 0.83-0.99 | .03 | 0.95 | 0.85-1.06 | .37 | 0.96 | 0.85-1.08 | .50 |
Age at interview, y | 1.14 | 1.08-1.19 | < .001 | 1.07 | 1.04-1.11 | < .001 | 1.26 | 1.29-1.41 | < .001 | 1.16 | 1.01-1.32 | .04 | 1.06 | 0.93-1.20 | .38 |
BMI | 1.13 | 1.09-1.18 | < .001 | 1.07 | 1.04-1.10 | < .001 | 0.98 | 0.87-1.09 | .66 | 0.99 | 0.87-1.12 | .83 | 0.92 | 0.79-1.08 | .32 |
NE indicates not estimable because no outcome in one or more categories; and Ref, reference category.