Frequencies and percentages of patient disease and characteristics in those with diabetes, hypertension, and cardiovascular events
| . | Diabetes . | Hypertension . | Arterial disease . | Myocardial infarction . | Stroke . | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | No. . | % . | No. . | % . | No. . | % . | No. . | % . | No. . | % . |
| Siblings | 12 | 3.1 | 57 | 14.9 | 6 | 1.6 | 3 | 0.8 | 1 | 0.3 |
| Survivors | 83 | 7.6 | 201 | 18.5 | 14 | 1.3 | 9 | 0.8 | 8 | 0.7 |
| Sex | ||||||||||
| Female | 30 | 36.1 | 86 | 42.8 | 1 | 7.1 | 4 | 44.4 | 4 | 50.0 |
| Male | 53 | 63.9 | 115 | 57.2 | 13 | 92.9 | 5 | 55.6 | 4 | 50.0 |
| Race/ethnicity | ||||||||||
| White | 54 | 65.1 | 171 | 85.1 | 14 | 100.0 | 8 | 88.9 | 8 | 100.0 |
| Hispanic | 20 | 24.1 | 20 | 10.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Other | 9 | 10.8 | 10 | 5.0 | 0 | 0.0 | 1 | 11.1 | 0 | 0.0 |
| Diagnosis | ||||||||||
| Acute leukemia | 33 | 39.8 | 56 | 27.9 | 5 | 35.7 | 4 | 44.4 | 4 | 50.0 |
| Chronic leukemia | 24 | 28.9 | 51 | 25.4 | 3 | 21.4 | 0 | 0.0 | 2 | 25.0 |
| Lymphoma | 21 | 25.3 | 64 | 31.8 | 6 | 42.9 | 5 | 55.6 | 1 | 12.5 |
| Aplastic anemia | 2 | 2.4 | 11 | 5.5 | 0 | 0.0 | 0 | 0.0 | 1 | 12.5 |
| Metabolic diseases | 0 | 0.0 | 5 | 2.5 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Immune disorder | 0 | 0.0 | 2 | 1.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Breast cancer | 0 | 0.0 | 1 | 0.5 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Sarcoma | 0 | 0.0 | 1 | 0.5 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Other | 3 | 3.6 | 9 | 4.5 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Transplant type | ||||||||||
| Autologous | 31 | 37.3 | 88 | 43.8 | 6 | 42.9 | 5 | 55.6 | 3 | 37.5 |
| Allogeneic | 52 | 62.7 | 113 | 56.2 | 8 | 57.1 | 4 | 44.4 | 5 | 62.5 |
| Stem-cell source | ||||||||||
| Bone marrow | 58 | 69.9 | 132 | 65.7 | 10 | 71.4 | 4 | 44.4 | 6 | 75.0 |
| Peripheral-blood stem cells | 24 | 28.9 | 67 | 33.3 | 4 | 28.6 | 5 | 55.6 | 2 | 25.0 |
| Cord blood | 1 | 1.2 | 2 | 1.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Conditioning regimen | ||||||||||
| Chemotherapy | 9 | 10.8 | 53 | 26.4 | 2 | 14.3 | 2 | 22.2 | 1 | 12.5 |
| TBI and chemotherapy | 74 | 89.2 | 148 | 73.6 | 12 | 85.7 | 7 | 77.8 | 7 | 87.5 |
| Chronic GVHD | ||||||||||
| No | 61 | 73.5 | 145 | 72.1 | 8 | 57.1 | 7 | 77.8 | 6 | 75.0 |
| Yes | 22 | 26.5 | 56 | 27.9 | 6 | 42.9 | 2 | 22.2 | 2 | 25.0 |
| Growth-hormone deficiency | ||||||||||
| No | 80 | 96.4 | 197 | 98.0 | 14 | 100.0 | 9 | 100.0 | 6 | 75.0 |
| Yes | 3 | 3.6 | 4 | 2.0 | 0 | 0.0 | 0 | 0.0 | 2 | 25.0 |
| . | Diabetes . | Hypertension . | Arterial disease . | Myocardial infarction . | Stroke . | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | No. . | % . | No. . | % . | No. . | % . | No. . | % . | No. . | % . |
| Siblings | 12 | 3.1 | 57 | 14.9 | 6 | 1.6 | 3 | 0.8 | 1 | 0.3 |
| Survivors | 83 | 7.6 | 201 | 18.5 | 14 | 1.3 | 9 | 0.8 | 8 | 0.7 |
| Sex | ||||||||||
| Female | 30 | 36.1 | 86 | 42.8 | 1 | 7.1 | 4 | 44.4 | 4 | 50.0 |
| Male | 53 | 63.9 | 115 | 57.2 | 13 | 92.9 | 5 | 55.6 | 4 | 50.0 |
| Race/ethnicity | ||||||||||
| White | 54 | 65.1 | 171 | 85.1 | 14 | 100.0 | 8 | 88.9 | 8 | 100.0 |
| Hispanic | 20 | 24.1 | 20 | 10.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Other | 9 | 10.8 | 10 | 5.0 | 0 | 0.0 | 1 | 11.1 | 0 | 0.0 |
| Diagnosis | ||||||||||
| Acute leukemia | 33 | 39.8 | 56 | 27.9 | 5 | 35.7 | 4 | 44.4 | 4 | 50.0 |
| Chronic leukemia | 24 | 28.9 | 51 | 25.4 | 3 | 21.4 | 0 | 0.0 | 2 | 25.0 |
| Lymphoma | 21 | 25.3 | 64 | 31.8 | 6 | 42.9 | 5 | 55.6 | 1 | 12.5 |
| Aplastic anemia | 2 | 2.4 | 11 | 5.5 | 0 | 0.0 | 0 | 0.0 | 1 | 12.5 |
| Metabolic diseases | 0 | 0.0 | 5 | 2.5 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Immune disorder | 0 | 0.0 | 2 | 1.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Breast cancer | 0 | 0.0 | 1 | 0.5 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Sarcoma | 0 | 0.0 | 1 | 0.5 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Other | 3 | 3.6 | 9 | 4.5 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Transplant type | ||||||||||
| Autologous | 31 | 37.3 | 88 | 43.8 | 6 | 42.9 | 5 | 55.6 | 3 | 37.5 |
| Allogeneic | 52 | 62.7 | 113 | 56.2 | 8 | 57.1 | 4 | 44.4 | 5 | 62.5 |
| Stem-cell source | ||||||||||
| Bone marrow | 58 | 69.9 | 132 | 65.7 | 10 | 71.4 | 4 | 44.4 | 6 | 75.0 |
| Peripheral-blood stem cells | 24 | 28.9 | 67 | 33.3 | 4 | 28.6 | 5 | 55.6 | 2 | 25.0 |
| Cord blood | 1 | 1.2 | 2 | 1.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Conditioning regimen | ||||||||||
| Chemotherapy | 9 | 10.8 | 53 | 26.4 | 2 | 14.3 | 2 | 22.2 | 1 | 12.5 |
| TBI and chemotherapy | 74 | 89.2 | 148 | 73.6 | 12 | 85.7 | 7 | 77.8 | 7 | 87.5 |
| Chronic GVHD | ||||||||||
| No | 61 | 73.5 | 145 | 72.1 | 8 | 57.1 | 7 | 77.8 | 6 | 75.0 |
| Yes | 22 | 26.5 | 56 | 27.9 | 6 | 42.9 | 2 | 22.2 | 2 | 25.0 |
| Growth-hormone deficiency | ||||||||||
| No | 80 | 96.4 | 197 | 98.0 | 14 | 100.0 | 9 | 100.0 | 6 | 75.0 |
| Yes | 3 | 3.6 | 4 | 2.0 | 0 | 0.0 | 0 | 0.0 | 2 | 25.0 |
For siblings, N = 383; for survivors, N = 1089.
TBI indicates total body irradiation.