Table 2

Response to induction and consolidation therapy

Good early respondersPoor early respondersAll patients
No. patients 14 31 45 
Early response, no. 
    CsS and ChS 14 14 
    CsR and ChS 
    CsS and ChR 17 17 
    CsR and ChR 
After standard induction, no. (%) 
    Hematologic CR 14 (100) NA NA 
    PCR negativity* 4 (29) NA NA 
Overall response to combined imatinib/chemotherapy, no. (%) 
    Hematologic CR 14 (100) 29 (94) 43 (96) 
    Low PCR level* 10 (71) 18 (58) 28 (62) 
    PCR negativity* 9 (64) 8 (26) 17 (38) 
Good early respondersPoor early respondersAll patients
No. patients 14 31 45 
Early response, no. 
    CsS and ChS 14 14 
    CsR and ChS 
    CsS and ChR 17 17 
    CsR and ChR 
After standard induction, no. (%) 
    Hematologic CR 14 (100) NA NA 
    PCR negativity* 4 (29) NA NA 
Overall response to combined imatinib/chemotherapy, no. (%) 
    Hematologic CR 14 (100) 29 (94) 43 (96) 
    Low PCR level* 10 (71) 18 (58) 28 (62) 
    PCR negativity* 9 (64) 8 (26) 17 (38) 

CsS indicates corticosensitive; ChS, chemosensitive; CsR, corticoresistant; ChR, chemoresistant; NA, not applicable.

*

As defined in “Patients and methods.”

After HAMI consolidation in good early responders and after DIV combination in poor early responders.

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