Table 5

Multivariate proportional hazards analysis for overall survival in test set (N = 234)

%Overall survival
HR95% CIP
MRI ≥ 1 focal lesion 71 3.31 1.64, 6.68 .001 
LDH ≥ upper limit of normal 21 2.27 1.35, 3.82 .002 
Subgroups with poor prognosis* 37 2.13 1.30, 3.48 .003 
Albumin < 3.5 g/dL 16 1.92 1.09, 3.37 .024 
Non-MGUS-like 71 2.23 1.08, 4.61 .030 
%Overall survival
HR95% CIP
MRI ≥ 1 focal lesion 71 3.31 1.64, 6.68 .001 
LDH ≥ upper limit of normal 21 2.27 1.35, 3.82 .002 
Subgroups with poor prognosis* 37 2.13 1.30, 3.48 .003 
Albumin < 3.5 g/dL 16 1.92 1.09, 3.37 .024 
Non-MGUS-like 71 2.23 1.08, 4.61 .030 

Two hundred thirty-four patients with complete data on all variables were available for the analysis. Only significant variables are shown. Seventy-four patients died.

*

Proliferation/MMSET/MAF.

Conversion factor for SI units: multiply albumin values by 10 for conversion to g/L.

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