ATF immunostaining in primary malignant and nonmalignant lymphoid tissue
. | ATF3 nuclear staining, no. cases . | . | |
|---|---|---|---|
. | Positive . | Negative . | |
| Classical Hodgkin lymphoma | 69 | 2 | |
| Lymphocyte-predominant Hodgkin lymphoma | 0 | 26 | |
| B-NHL | 6* | 233 | |
| T-NHL | 2† | 44 | |
| Anaplastic large cell lymphoma (ALCL) | 24 | 9 | |
| Reactive lymphatic tissue | 0 | 20 | |
. | ATF3 nuclear staining, no. cases . | . | |
|---|---|---|---|
. | Positive . | Negative . | |
| Classical Hodgkin lymphoma | 69 | 2 | |
| Lymphocyte-predominant Hodgkin lymphoma | 0 | 26 | |
| B-NHL | 6* | 233 | |
| T-NHL | 2† | 44 | |
| Anaplastic large cell lymphoma (ALCL) | 24 | 9 | |
| Reactive lymphatic tissue | 0 | 20 | |
Summary of ATF3 immunohistochemistry results. The group of B-cell non-Hodgkin lymphomas (B-NHLs) includes 21 mantle cell lymphomas (MCLs), 27 B-cell chronic lymphocytic leukemias (B-CLLs), 72 follicular lymphomas (FLs), 80 diffuse large B-cell lymphomas (DLBCLs, including 6 primary mediastinal B-cell lymphomas), 19 Burkitt lymphomas (BLs), and 20 plasmacytomas. T-cell non-Hodgkin lymphomas (T-NHLs) comprise 20 peripheral T-NHLs (PTCLs), 10 angioimmunoblastic T-NHLs (AILTs), 5 enteropathy-associated T-NHLs, 4 NK/T-cell lymphomas, and 7 cases of mycosis fungoides.
Two cases of DLBCL (one centroblastic variant and one primary mediastinal B cell lymphoma), 4 cases of plasmacytoma.
Two cases of angioimmunoblastic T-cell lymphoma (AILT), nuclear ATF3 staining in malignant T cells.