Effect of EM011 on the cell cycle progression of CEM/VLB100 cells
. | CEM/VLB100 cells, % . | . | . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|
Cell cycle phase . | 0 h . | 12 h . | 24 h . | 48 h . | 72 h . | ||||
G0/G1 | 41.45 ± 3.63 | 18.33 ± 0.98 | 16.12 ± 0.99 | 11.80 ± 1.11 | 6.37 ± 0.86 | ||||
S | 26.34 ± 1.89 | 17.93 ± 1.18 | 24.19 ± 1.44 | 12.32 ± 1.78 | 9.91 ± 1.37 | ||||
G2/M | 33.29 ± 2.20 | 46.75 ± 2.22 | 24.73 ± 1.38 | 9.39 ± 0.88 | 6.41 ± 0.86 | ||||
Sub-G1 | 0.88 ± 0.10 | 17.81 ± 1.77 | 27.87 ± 2.20 | 63.47 ± 5.47 | 75.17 ± 6.32 |
. | CEM/VLB100 cells, % . | . | . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|
Cell cycle phase . | 0 h . | 12 h . | 24 h . | 48 h . | 72 h . | ||||
G0/G1 | 41.45 ± 3.63 | 18.33 ± 0.98 | 16.12 ± 0.99 | 11.80 ± 1.11 | 6.37 ± 0.86 | ||||
S | 26.34 ± 1.89 | 17.93 ± 1.18 | 24.19 ± 1.44 | 12.32 ± 1.78 | 9.91 ± 1.37 | ||||
G2/M | 33.29 ± 2.20 | 46.75 ± 2.22 | 24.73 ± 1.38 | 9.39 ± 0.88 | 6.41 ± 0.86 | ||||
Sub-G1 | 0.88 ± 0.10 | 17.81 ± 1.77 | 27.87 ± 2.20 | 63.47 ± 5.47 | 75.17 ± 6.32 |
Cells were treated with 10 μM EM011 for the indicated time (h) before being stained with Pl for cell cycle analysis. Values shown are mean ± SEM.