Effect of EM011 on the cell cycle progression of CEM cells
. | CEM cells, % . | . | . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|
Cell cycle phase . | 0 h . | 12 h . | 24 h . | 48 h . | 72 h . | ||||
G0/G1 | 46.75 ± 4.12 | 22.12 ± 0.68 | 23.98 ± 2.87 | 15.32 ± 1.11 | 10.79 ± 1.76 | ||||
S | 24.71 ± 3.18 | 20.82 ± 1.23 | 17.45 ± 1.32 | 12.22 ± 1.71 | 8.73 ± 0.88 | ||||
G2/M | 24.75 ± 2.78 | 45.13 ± 3.19 | 31.00 ± 1.71 | 16.28 ± 2.18 | 11.86 ± 0.97 | ||||
Sub-G1 | 1.98 ± 0.23 | 15.17 ± 1.45 | 20.16 ± 2.21 | 47.89 ± 5.08 | 57.68 ± 5.18 |
. | CEM cells, % . | . | . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|
Cell cycle phase . | 0 h . | 12 h . | 24 h . | 48 h . | 72 h . | ||||
G0/G1 | 46.75 ± 4.12 | 22.12 ± 0.68 | 23.98 ± 2.87 | 15.32 ± 1.11 | 10.79 ± 1.76 | ||||
S | 24.71 ± 3.18 | 20.82 ± 1.23 | 17.45 ± 1.32 | 12.22 ± 1.71 | 8.73 ± 0.88 | ||||
G2/M | 24.75 ± 2.78 | 45.13 ± 3.19 | 31.00 ± 1.71 | 16.28 ± 2.18 | 11.86 ± 0.97 | ||||
Sub-G1 | 1.98 ± 0.23 | 15.17 ± 1.45 | 20.16 ± 2.21 | 47.89 ± 5.08 | 57.68 ± 5.18 |
Cells were treated with 10 μM EM011 for the indicated time (h) before being stained with PI for cell cycle analysis. Values shown are mean ± SEM.