Table 1.

Effect of EM011 on the cell cycle progression of CEM cells



CEM cells, %
Cell cycle phase
0 h
12 h
24 h
48 h
72 h
G0/G1  46.75 ± 4.12   22.12 ± 0.68   23.98 ± 2.87   15.32 ± 1.11   10.79 ± 1.76  
S   24.71 ± 3.18   20.82 ± 1.23   17.45 ± 1.32   12.22 ± 1.71   8.73 ± 0.88  
G2/M   24.75 ± 2.78   45.13 ± 3.19   31.00 ± 1.71   16.28 ± 2.18   11.86 ± 0.97  
Sub-G1
 
1.98 ± 0.23
 
15.17 ± 1.45
 
20.16 ± 2.21
 
47.89 ± 5.08
 
57.68 ± 5.18
 


CEM cells, %
Cell cycle phase
0 h
12 h
24 h
48 h
72 h
G0/G1  46.75 ± 4.12   22.12 ± 0.68   23.98 ± 2.87   15.32 ± 1.11   10.79 ± 1.76  
S   24.71 ± 3.18   20.82 ± 1.23   17.45 ± 1.32   12.22 ± 1.71   8.73 ± 0.88  
G2/M   24.75 ± 2.78   45.13 ± 3.19   31.00 ± 1.71   16.28 ± 2.18   11.86 ± 0.97  
Sub-G1
 
1.98 ± 0.23
 
15.17 ± 1.45
 
20.16 ± 2.21
 
47.89 ± 5.08
 
57.68 ± 5.18
 

Cells were treated with 10 μM EM011 for the indicated time (h) before being stained with PI for cell cycle analysis. Values shown are mean ± SEM.

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