Table 1.

CD38 cocapping with MDDC membrane receptors and lipid domain-associated molecules


Cap and cocap

Caps, %

Cocaps, %
Associated molecules   
    CD38 and CD11b 86 80 
    CD11b and CD38   90   88  
    CD38 and CD83 79 73 
    CD83 and CD38   86   69  
    CCR7 and CD38 38 66 
Nonassociated molecules   
    CD38 and CD31 90 15 
    CD38 and CD80   88   9  
    CD38 and DC-SIGN 87 7 
    CD38 and CD86   75   9  
Lipid domain-associated molecules   
    CD38 and CTX 69 62 
    CD38 and CD81   75   54  
    CD81 and CD38
 
78
 
68
 

Cap and cocap

Caps, %

Cocaps, %
Associated molecules   
    CD38 and CD11b 86 80 
    CD11b and CD38   90   88  
    CD38 and CD83 79 73 
    CD83 and CD38   86   69  
    CCR7 and CD38 38 66 
Nonassociated molecules   
    CD38 and CD31 90 15 
    CD38 and CD80   88   9  
    CD38 and DC-SIGN 87 7 
    CD38 and CD86   75   9  
Lipid domain-associated molecules   
    CD38 and CTX 69 62 
    CD38 and CD81   75   54  
    CD81 and CD38
 
78
 
68
 

Cumulative data from 3 independent experiments are shown. The number of caps and cocaps are presented as a percentage of the cells analyzed. Cells exhibiting partial redistribution of the surface molecule detected by the primary capping antibody were excluded from the analysis.

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