Table 6 Production of IL-10 and TGF-β by... | American Society of Hematology

Table 6

Production of IL-10 and TGF-β by CD4⁺CD25⁻ T lymphocytes and CD4⁺CD25⁺ regulatory T cells

	CD4⁺CD25⁻		CD4⁺CD25⁺
	Control	Reserpine	Control	Reserpine
IL-10, pg/mL	6.05 ± 4.70	5.49 ± 3.39	111.58 ± 10.58*	63.91 ± 12.36†
TGF-β, pg/mL	3.09 ± 1.89	3.74 ± 1.61	41.07 ± 8.70*	18.09 ± 5.81†

	CD4⁺CD25⁻		CD4⁺CD25⁺
	Control	Reserpine	Control	Reserpine
IL-10, pg/mL	6.05 ± 4.70	5.49 ± 3.39	111.58 ± 10.58*	63.91 ± 12.36†
TGF-β, pg/mL	3.09 ± 1.89	3.74 ± 1.61	41.07 ± 8.70*	18.09 ± 5.81†

Cells were cultured for 48 hours under standard conditions in the absence or in the presence of 1 μM reserpine. Data are mean α SD of 9 separate observations.

P < .001 versus CD4⁺CD25⁻.

†

P < .01 versus respective control.

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