Engraftment characteristics of unsorted ALL cells in NOD/SCID mice
Patient no. . | % CD45+ in NOD/SCID*, by no. of unsorted cells injected . | % FISH+ . | |||
---|---|---|---|---|---|
5 × 105 . | 1 × 106 . | 5 × 106 . | 1 × 107 . | ||
2 | — | 54.0 | 82.0 | 99.0 | NA |
4 | — | 1.0 | 2.0 | 6.0 | NA |
6 | 59 | 80.0 | 91.0 | 98.0 | 100 |
7 | — | — | — | 0.2 | NA |
10 | — | 0.4 | 2.6 | — | NA |
12 | 2 | 60.0 | 89.0 | — | — |
13 | — | — | 38.0 | — | 50 |
13† | — | — | 83.0 | — | 48 |
13‡ | — | — | 55.0 | 96.0 | 53 |
14 | — | 25.0 | 41.0 | 79.0 | 71 |
15† | — | 0.5 | 11.0 | — | 82 |
16 | — | 0.3 | 26.0 | — | 68 |
Patient no. . | % CD45+ in NOD/SCID*, by no. of unsorted cells injected . | % FISH+ . | |||
---|---|---|---|---|---|
5 × 105 . | 1 × 106 . | 5 × 106 . | 1 × 107 . | ||
2 | — | 54.0 | 82.0 | 99.0 | NA |
4 | — | 1.0 | 2.0 | 6.0 | NA |
6 | 59 | 80.0 | 91.0 | 98.0 | 100 |
7 | — | — | — | 0.2 | NA |
10 | — | 0.4 | 2.6 | — | NA |
12 | 2 | 60.0 | 89.0 | — | — |
13 | — | — | 38.0 | — | 50 |
13† | — | — | 83.0 | — | 48 |
13‡ | — | — | 55.0 | 96.0 | 53 |
14 | — | 25.0 | 41.0 | 79.0 | 71 |
15† | — | 0.5 | 11.0 | — | 82 |
16 | — | 0.3 | 26.0 | — | 68 |