Clinical and laboratory characteristics of the patients
| Characteristic . | Value . |
|---|---|
| No. of patients | 90 |
| Sex, no. | |
| Male | 54 |
| Female | 36 |
| Median age, y (range) | 62.5 (18-93) |
| FAB classification, no. | |
| M0 | 7 |
| M1 | 10 |
| M2 | 12 |
| M3 | 1 |
| M4 | 27 |
| M5 | 7 |
| M6 | 0 |
| M7 | 2 |
| MDS | 7 |
| Undefined by FAB | 17 |
| Cytogenetic abnormality, no. | |
| Favorable | 7 |
| Intermediate | 47 |
| Unfavorable | 26 |
| Unknown | 10 |
| Median WBC count, × 109/L (range) | 13.5 (0.5-300) |
| Median LDH level, U/L (range) | 328 (140-2760) |
| Median platelet count, × 109/L (range) | 70 (4-265) |
| Median % of CXCR4+ blasts (range) | 61.2 (4.7-100) |
| Median CXCR4, MFIR (range) | 6.9 (1.2-73.4) |
| Median time to follow-up, mo (range) | 13 (0-55) |
| Characteristic . | Value . |
|---|---|
| No. of patients | 90 |
| Sex, no. | |
| Male | 54 |
| Female | 36 |
| Median age, y (range) | 62.5 (18-93) |
| FAB classification, no. | |
| M0 | 7 |
| M1 | 10 |
| M2 | 12 |
| M3 | 1 |
| M4 | 27 |
| M5 | 7 |
| M6 | 0 |
| M7 | 2 |
| MDS | 7 |
| Undefined by FAB | 17 |
| Cytogenetic abnormality, no. | |
| Favorable | 7 |
| Intermediate | 47 |
| Unfavorable | 26 |
| Unknown | 10 |
| Median WBC count, × 109/L (range) | 13.5 (0.5-300) |
| Median LDH level, U/L (range) | 328 (140-2760) |
| Median platelet count, × 109/L (range) | 70 (4-265) |
| Median % of CXCR4+ blasts (range) | 61.2 (4.7-100) |
| Median CXCR4, MFIR (range) | 6.9 (1.2-73.4) |
| Median time to follow-up, mo (range) | 13 (0-55) |
Favorable includes t(8;21), t(15,17), inv 16; intermediate, normal karyotype, other; and unfavorable, −5, −7, t(6;9), (11q23) abn., complex.