Table 1

Summary of the transforming properties of EEN

Cell lineGrowth in soft agar, no. per 1000 cells*Tumor formation in nude mice, no. positive / no. of injection sites
NIH3T3-GFP 0.0 ± 0.0 0/5 
NIH3T3-EEN 109.0 ± 35.4 6/6 
Cell lineGrowth in soft agar, no. per 1000 cells*Tumor formation in nude mice, no. positive / no. of injection sites
NIH3T3-GFP 0.0 ± 0.0 0/5 
NIH3T3-EEN 109.0 ± 35.4 6/6 

*The values for soft agar colonies are means ± standard deviations of 4 separate experiments.

†Tumors (+) were at least 1 cm in diameter after 6 weeks.

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