Patient characteristics
. | All . | HLA-matched related . | Unrelated . | HLA-mismatched related . |
|---|---|---|---|---|
| Patient no. | 292 | 191 | 74 | 27 |
| Sex, % female | 38.4 | 36.9 | 47.1 | 33.3 |
| Age, median, y (range) | 24.0 (0.2-69.0) | 31.5 (0.2-69.0) | 17.3 (0.6-55.5) | 6.0 (0.2-46.8) |
| No. of children per group (%) | 116/291 (40.2) | 56/190 (29.5) | 38/74 (51.4) | 22/27 (81.5) |
| Diagnosis | ||||
| Acute leukemia | 124 | 76 | 42 | 7 |
| Chronic leukemia | 72 | 57 | 11 | 4 |
| Aplastic anemia/MDS | 41 | 23 | 12 | 6 |
| NHL/HD | 28 | 19 | 7 | 1 |
| Hemoglobinopathy | 10 | 10 | 0 | 0 |
| Immunodeficiency | 17 | 6 | 2 | 9 |
| Stem-cell product (%) | ||||
| Unmodified | 102 (35.1) | 71 (37.3) | 24 (27.0) | 7 (25.9) |
| Bone marrow | 88 | 64 | 19 | 6 |
| PBSCs | 13 | 8 | 4 | 1 |
| Cord blood | 1 | 0 | 1 | 0 |
| TCD | 179 (65.7) | 119 (65.7) | 50 (67.6) | 20 (74.1) |
| Bone marrow | 153 | 102 | 41 | 10 |
| PBSCs | 26 | 17 | 9 | 10 |
| TBI-containing regimen, % | 76.9 | 74.3 | 88 | 55.6 |
. | All . | HLA-matched related . | Unrelated . | HLA-mismatched related . |
|---|---|---|---|---|
| Patient no. | 292 | 191 | 74 | 27 |
| Sex, % female | 38.4 | 36.9 | 47.1 | 33.3 |
| Age, median, y (range) | 24.0 (0.2-69.0) | 31.5 (0.2-69.0) | 17.3 (0.6-55.5) | 6.0 (0.2-46.8) |
| No. of children per group (%) | 116/291 (40.2) | 56/190 (29.5) | 38/74 (51.4) | 22/27 (81.5) |
| Diagnosis | ||||
| Acute leukemia | 124 | 76 | 42 | 7 |
| Chronic leukemia | 72 | 57 | 11 | 4 |
| Aplastic anemia/MDS | 41 | 23 | 12 | 6 |
| NHL/HD | 28 | 19 | 7 | 1 |
| Hemoglobinopathy | 10 | 10 | 0 | 0 |
| Immunodeficiency | 17 | 6 | 2 | 9 |
| Stem-cell product (%) | ||||
| Unmodified | 102 (35.1) | 71 (37.3) | 24 (27.0) | 7 (25.9) |
| Bone marrow | 88 | 64 | 19 | 6 |
| PBSCs | 13 | 8 | 4 | 1 |
| Cord blood | 1 | 0 | 1 | 0 |
| TCD | 179 (65.7) | 119 (65.7) | 50 (67.6) | 20 (74.1) |
| Bone marrow | 153 | 102 | 41 | 10 |
| PBSCs | 26 | 17 | 9 | 10 |
| TBI-containing regimen, % | 76.9 | 74.3 | 88 | 55.6 |
MDS indicates myelodysplastic syndrome; NHL/HD, non-Hodgkin lymphoma/Hodgkin disease; PBSCs, peripheral-blood stem cells; and TBI, total body irradiation.