Table 1. Effect of human serum on the... | American Society of Hematology

Table 1.

Effect of human serum on the influx of radio-labeled choline, sorbitol, and lactate in malaria-infected RBCs

	Parasitemia-corrected NPPB-sensitive influx, mmol/(10¹² cells/h)
Substrate	Without serum	With serum	Student paired, 2-tailed t test
Choline
37°C	0.23 ± 0.01	0.21 ± 0.01	0.33
RT	0.064 ± 0.005	0.067 ± 0.008	0.50
Ratio_37/RT	3.6	3.1	—
Sorbitol
37°C	2.3 ± 0.2	2.2 ± 0.2	0.25
RT	0.69 ± 0.08	0.68 ± 0.05	0.94
Ratio_37/RT	3.3	3.2	—
Lactate
RT	57 ± 2	62 ± 1	0.19

	Parasitemia-corrected NPPB-sensitive influx, mmol/(10¹² cells/h)
Substrate	Without serum	With serum	Student paired, 2-tailed t test
Choline
37°C	0.23 ± 0.01	0.21 ± 0.01	0.33
RT	0.064 ± 0.005	0.067 ± 0.008	0.50
Ratio_37/RT	3.6	3.1	—
Sorbitol
37°C	2.3 ± 0.2	2.2 ± 0.2	0.25
RT	0.69 ± 0.08	0.68 ± 0.05	0.94
Ratio_37/RT	3.3	3.2	—
Lactate
RT	57 ± 2	62 ± 1	0.19

Human serum was present at a concentration of ≥ 1% vol/vol, and the data are presented as the mean ± SEM (n = 3).

— indicates not applicable.