Table 1. sCD40L concentrations in blood... | American Society of Hematology

Table 1.

sCD40L concentrations in blood components

	sCD40L, ng/mL
Blood components	Nonimplicated TRALI, U	Implicated TRALI, U
FP from healthy donors	0.01 ± 0.003	N/A
FFP	1.3 ± 0.13*	N/A
WB-Plts	7.9 ± 1.1*	14.0 ± 3.0*†
A-Plts	11.8 ± 0.82*	44.7 ± 4.5*†

	sCD40L, ng/mL
Blood components	Nonimplicated TRALI, U	Implicated TRALI, U
FP from healthy donors	0.01 ± 0.003	N/A
FFP	1.3 ± 0.13*	N/A
WB-Plts	7.9 ± 1.1*	14.0 ± 3.0*†
A-Plts	11.8 ± 0.82*	44.7 ± 4.5*†

N/A indicates not applicable.

P < .05 from FP obtained through venipuncture from 5 healthy subjects.

†

P < .05 from WB-Plt concentrates that did not cause a transfusion reaction or from 5 A-Plt concentrates from healthy donors, respectively. Soluble CD40L concentrations were measured in duplicate by commercial human sCD40 ELISA. Numbers of units tested in all categories were as follows: 5 U FP, 10 U FFP, 57 samples from WB-Plt concentrates that did not cause transfusion reactions, 62 samples from WB-Plt concentrates implicated in TRALI, 5 U A-Plts from healthy donors, and 29 samples from A-Plt concentrates implicated in TRALI.

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