Table 1.

Putative c-Rel targets derived from expression profiling of EDI MoDCs


Sequence name

Sequence code

Accession no.

Sequence description

Function
DKFZP586D0919  39986_at   AL050100   Hepatocellularcarcinoma-associated antigen HCA557a   Unknown  
GRAMD1B  41559_at   AA434319   GRAM domain containing 1B   Unknown  
HYAL3  35540_at   AF040710   Hyaluronidase (LUCA-3) mRNA   Unknown  
JRK  37873_g_at   AF072468   Jerky homolog (mouse)   Unknown  
LOC221362  37538_at   AL049354   Hypothetical protein LOC221362   Unknown  
MAC30  32791_at   L19183   Hypothetical protein MAC30   Unknown  
NBEAL2  35763_at   AB011112   Neurobeachin-like 2   Unknown  
PHLPPL  32735_at   AB023148   PH domain and leucine rich repeat protein phosphatase-like   Unknown  
LAD1  33282_at   U42408   Ladinin 1   Adhesion and extracellular matrix  
LAMB3  36929_at   U17760   Laminin, beta 3   Adhesion and extracellular matrix  
PLAT  33452_at   M15518   Plasminogen activator, tissue   Adhesion and extracellular matrix  
SERPINE1  38125_at   M14083   Serine proteinase inhibitor, clade E (plasminogen activator inhibitor type 1), member 1   Adhesion and extracellular matrix  
ST8SIA1  40678_at   X77922   ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1   Adhesion and extracellular matrix  
TPST1  32718_at   AF038009   Tyrosylprotein sulfotransferase 1   Adhesion and extracellular matrix  
BCL2L1  34742_at   Z23115   BCL2-like 1   Apoptosis  
HTATIP  465_at   U74667   HIV-1 Tat interactive protein, 60 kDa   Apoptosis  
AVIL  41582_at   AF041449   Advillin   Cytoskeleton  
CAPG  38391_at   M94345   Capping protein (actin filament), gelsolin-like   Cytoskeleton  
DLGAP1  40388_at   AB000277   Discs, large (Drosophila) homolog-associated protein 1   Cytoskeleton  
SEPT11  33172_at   T75292   Septin 11   Cytoskeleton  
TIAM1  37460_at   U16296   T-cell lymphoma invasion and metastasis 1   Cytoskeleton  
ACVR2A  35162_s_at   D31770   Activin A receptor, type II   Growth and differentiation  
ACVRL1  32714_s_at   L17075   Activin A receptor type II-like 1   Growth and differentiation  
CDK7  1969_s_at   X77743   Cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)   Growth and differentiation  
IL12A  33955_at   M65291   Interleukin 12A (cytotoxic lymphocyte maturation factor 1, p35)   Growth and differentiation  
MELK  38847_at   D79997   Maternal embryonic leucine zipper kinase   Growth and differentiation  
VEGF  36101_s_at   M63978   Vascular endothelial growth factor   Growth and differentiation  
ACOX1  40460_s_at   X71440   Acyl-Coenzyme A oxidase 1, palmitoyl   Metabolism  
B4GALT4  39432_at   AF038662   UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4   Metabolism  
GALT  36664_at   M60091   Galactose-1-phosphate uridylyltransferase   Metabolism  
MTHFS  39064_at   L38928   5,10-methenyltetrahydrofolate synthetase   Metabolism  
PRKAB1  35348_at   AF022116   Protein kinase, AMP-activated, beta 1 noncatalytic subunit   Metabolism  
SLC25A1  38998_g_at   X96924   Solute carrier family 25 (citrate transporter), member 1   Metabolism  
SLC5A6  35256_at   AL096737   Solute carrier family 5 (sodium-dependent vitamin transporter), member 6   Metabolism  
SMS  38792_at   AD001528   Spermine synthase   Metabolism  
DUSP2  1292_at   L11329   Dual specificity phosphatase 2   Signaling  
GRIA3  35050_at   X82068   Glutamate receptor, ionotrophic, AMPA 3   Signaling  
ITPR3  37343_at   U01062   Inositol 1,4,5-triphosphate receptor, type 3   Signaling  
PCTK1  1224_at   X66363   PCTAIRE protein kinase 1   Signaling  
PVR  32698_at   X64116   PVR gene for poliovirus receptor   Signaling  
RAB30  807_at   U57092   RAB30, member RAS oncogene family   Signaling  
TNFRSF14  39424_at   U70321   TNF receptor superfamily, member 14   Signaling  
TRG@  41468_at   M30894   T-cell receptor gamma locus   Signaling  
ELL2  40606_at   U88629   RNA polymerase II elongation factor   Transcription  
KLF7  34217_at   AB015132   Kruppel-like factor 7 (ubiquitous)   Transcription  
SMAD6  1955_s_at   AF035528   SMAD, mothers against DPP homolog 6 (Drosophila)   Transcription  
TSC22D3  36629_at   AI635895   TSC22 domain family, member 3   Transcription  
TTF2  37870_at   AF073771   Transcription termination factor, RNA polymerase II   Transcription  
EEF1A1  1288_s_at   J04617   Eurkaryotic translation elongation factor 1 alpha 1   Translation  
TSR1
 
40982_at
 
AA926957
 
TSR1, 20S rRNA accumualtion, homolog (yeast)
 
Translation
 

Sequence name

Sequence code

Accession no.

Sequence description

Function
DKFZP586D0919  39986_at   AL050100   Hepatocellularcarcinoma-associated antigen HCA557a   Unknown  
GRAMD1B  41559_at   AA434319   GRAM domain containing 1B   Unknown  
HYAL3  35540_at   AF040710   Hyaluronidase (LUCA-3) mRNA   Unknown  
JRK  37873_g_at   AF072468   Jerky homolog (mouse)   Unknown  
LOC221362  37538_at   AL049354   Hypothetical protein LOC221362   Unknown  
MAC30  32791_at   L19183   Hypothetical protein MAC30   Unknown  
NBEAL2  35763_at   AB011112   Neurobeachin-like 2   Unknown  
PHLPPL  32735_at   AB023148   PH domain and leucine rich repeat protein phosphatase-like   Unknown  
LAD1  33282_at   U42408   Ladinin 1   Adhesion and extracellular matrix  
LAMB3  36929_at   U17760   Laminin, beta 3   Adhesion and extracellular matrix  
PLAT  33452_at   M15518   Plasminogen activator, tissue   Adhesion and extracellular matrix  
SERPINE1  38125_at   M14083   Serine proteinase inhibitor, clade E (plasminogen activator inhibitor type 1), member 1   Adhesion and extracellular matrix  
ST8SIA1  40678_at   X77922   ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1   Adhesion and extracellular matrix  
TPST1  32718_at   AF038009   Tyrosylprotein sulfotransferase 1   Adhesion and extracellular matrix  
BCL2L1  34742_at   Z23115   BCL2-like 1   Apoptosis  
HTATIP  465_at   U74667   HIV-1 Tat interactive protein, 60 kDa   Apoptosis  
AVIL  41582_at   AF041449   Advillin   Cytoskeleton  
CAPG  38391_at   M94345   Capping protein (actin filament), gelsolin-like   Cytoskeleton  
DLGAP1  40388_at   AB000277   Discs, large (Drosophila) homolog-associated protein 1   Cytoskeleton  
SEPT11  33172_at   T75292   Septin 11   Cytoskeleton  
TIAM1  37460_at   U16296   T-cell lymphoma invasion and metastasis 1   Cytoskeleton  
ACVR2A  35162_s_at   D31770   Activin A receptor, type II   Growth and differentiation  
ACVRL1  32714_s_at   L17075   Activin A receptor type II-like 1   Growth and differentiation  
CDK7  1969_s_at   X77743   Cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)   Growth and differentiation  
IL12A  33955_at   M65291   Interleukin 12A (cytotoxic lymphocyte maturation factor 1, p35)   Growth and differentiation  
MELK  38847_at   D79997   Maternal embryonic leucine zipper kinase   Growth and differentiation  
VEGF  36101_s_at   M63978   Vascular endothelial growth factor   Growth and differentiation  
ACOX1  40460_s_at   X71440   Acyl-Coenzyme A oxidase 1, palmitoyl   Metabolism  
B4GALT4  39432_at   AF038662   UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4   Metabolism  
GALT  36664_at   M60091   Galactose-1-phosphate uridylyltransferase   Metabolism  
MTHFS  39064_at   L38928   5,10-methenyltetrahydrofolate synthetase   Metabolism  
PRKAB1  35348_at   AF022116   Protein kinase, AMP-activated, beta 1 noncatalytic subunit   Metabolism  
SLC25A1  38998_g_at   X96924   Solute carrier family 25 (citrate transporter), member 1   Metabolism  
SLC5A6  35256_at   AL096737   Solute carrier family 5 (sodium-dependent vitamin transporter), member 6   Metabolism  
SMS  38792_at   AD001528   Spermine synthase   Metabolism  
DUSP2  1292_at   L11329   Dual specificity phosphatase 2   Signaling  
GRIA3  35050_at   X82068   Glutamate receptor, ionotrophic, AMPA 3   Signaling  
ITPR3  37343_at   U01062   Inositol 1,4,5-triphosphate receptor, type 3   Signaling  
PCTK1  1224_at   X66363   PCTAIRE protein kinase 1   Signaling  
PVR  32698_at   X64116   PVR gene for poliovirus receptor   Signaling  
RAB30  807_at   U57092   RAB30, member RAS oncogene family   Signaling  
TNFRSF14  39424_at   U70321   TNF receptor superfamily, member 14   Signaling  
TRG@  41468_at   M30894   T-cell receptor gamma locus   Signaling  
ELL2  40606_at   U88629   RNA polymerase II elongation factor   Transcription  
KLF7  34217_at   AB015132   Kruppel-like factor 7 (ubiquitous)   Transcription  
SMAD6  1955_s_at   AF035528   SMAD, mothers against DPP homolog 6 (Drosophila)   Transcription  
TSC22D3  36629_at   AI635895   TSC22 domain family, member 3   Transcription  
TTF2  37870_at   AF073771   Transcription termination factor, RNA polymerase II   Transcription  
EEF1A1  1288_s_at   J04617   Eurkaryotic translation elongation factor 1 alpha 1   Translation  
TSR1
 
40982_at
 
AA926957
 
TSR1, 20S rRNA accumualtion, homolog (yeast)
 
Translation
 

Sequence names correspond to Human Genome Organization (HUGO) symbols retrieved from the National Center for Biotechnology Information (NCBI) database (www.ncbi.nlm.nih.gov/database/). Sequence codes refer to Affymetrix U95A probe set identifiers. Functions were assigned through reference to Entrez annotations (NCBI) and PubMed literature searches.

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