Table 4.

Differentiation potential of paired secondary clones




Clone type, no. (%)
Mouse
No. of clones
MTB-MTB
MTB-MB
MTB-TB
MTB-TB
T-B
101   22   12 (54.5)   5 (22.7)   1 (4.5)   3 (13.6)   1 (4.4)  
109   11   9 (81.8)   2 (18.2)   0 (0)   0 (0)   0 (0)  
113   10   6 (60)   2 (20)   2 (20)   0 (0)   0 (0)  
Total
 
43
 
27 (62.8)
 
9 (20.9)
 
3 (7)
 
3 (7)
 
1 (2.3)
 



Clone type, no. (%)
Mouse
No. of clones
MTB-MTB
MTB-MB
MTB-TB
MTB-TB
T-B
101   22   12 (54.5)   5 (22.7)   1 (4.5)   3 (13.6)   1 (4.4)  
109   11   9 (81.8)   2 (18.2)   0 (0)   0 (0)   0 (0)  
113   10   6 (60)   2 (20)   2 (20)   0 (0)   0 (0)  
Total
 
43
 
27 (62.8)
 
9 (20.9)
 
3 (7)
 
3 (7)
 
1 (2.3)
 

Differentiation potential of paired secondary clones was determined by PCR tracking strategy based on integration site analysis of DP cells developed in secondary recipients.

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