Differentiation potential of thymus-repopulating SRC clones
. | . | Clone type, no. (%) . | . | . | ||
|---|---|---|---|---|---|---|
| Mouse . | No. of clones . | MTB . | TB . | T . | ||
| 1 | 5 | 3 (60) | 1 (20) | 1 (20) | ||
| 3 | 12 | 7 (58.3) | 4 (33.3) | 1 (8.3) | ||
| 4 | 10 | 9 (90) | 1 (10) | 0 (0) | ||
| Total | 27 | 19 (70.4) | 6 (22.2) | 2 (7.4) | ||
. | . | Clone type, no. (%) . | . | . | ||
|---|---|---|---|---|---|---|
| Mouse . | No. of clones . | MTB . | TB . | T . | ||
| 1 | 5 | 3 (60) | 1 (20) | 1 (20) | ||
| 3 | 12 | 7 (58.3) | 4 (33.3) | 1 (8.3) | ||
| 4 | 10 | 9 (90) | 1 (10) | 0 (0) | ||
| Total | 27 | 19 (70.4) | 6 (22.2) | 2 (7.4) | ||
Lineage contribution of individual thymus-repopulating SRC clones was evaluated by PCR tracking based on integration site analysis of DP cells. No clones were differentiated into M and T lineages.
MTB indicates clones that gave rise to myeloid (M), T-lymphoid (T), and B-lymphoid (B) lineages; TB, clones differentiated into T and B lineages; T, clones differentiated into T lineage only.