Table 3.

Summary of disease in NRASD12 secondary transferred mice


Primary mouse no.

Disease in primary mouse

Disease type in secondary transfer mice (range of disease latency, d)
2-7   AML   3/4 AML (53-55); 1/4 ND  
2-8   AML   1/4 AML; 2/4 TLL (69-72); 1/4 ND  
2-10   AML   2/4 AML; 2/4 ND (81-83)  
4   AML   2/4 AML; 1/4 CMML (45-66); 1/4 ND  
7   CMML   2/4 AML; 1/4 CMML (50-119); 1/4 ND  
9
 
CMML
 
2/4 AML; 1/4 CMML (75-109); 1/4 ND
 

Primary mouse no.

Disease in primary mouse

Disease type in secondary transfer mice (range of disease latency, d)
2-7   AML   3/4 AML (53-55); 1/4 ND  
2-8   AML   1/4 AML; 2/4 TLL (69-72); 1/4 ND  
2-10   AML   2/4 AML; 2/4 ND (81-83)  
4   AML   2/4 AML; 1/4 CMML (45-66); 1/4 ND  
7   CMML   2/4 AML; 1/4 CMML (50-119); 1/4 ND  
9
 
CMML
 
2/4 AML; 1/4 CMML (75-109); 1/4 ND
 

ND indicates not determined; TLL, T-cell leukemia and lymphoma.

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