Overview of CDR3 sequences of CMV-specific CD4+ T cells from patient 1
Specific Vβ family and CDR3* . | Jβ† . | IFNγ+, wk 9‡ . | IFNγ+, wk 53‡ . | CD28-, wk 36‡ . |
|---|---|---|---|---|
| 3 | ||||
| CASSPTSNWGGWTEAFF | 1.101 | 1/4 | — | — |
| CASSLFGLASTDTQYF | 2.301 | — | 7/7 | — |
| CASSLGPAGLAKNIQYF | 2.401 | 1/4 | — | — |
| CASRRGKETQYF | 2.501 | 1/4 | — | — |
| CASKAPLGEQYF | 2.701 | 1/4 | — | — |
| 6.1 | ||||
| CASSKVDTEAFF | 1.101 | — | — | 2/23 |
| CASSTRQGGTEAFF | 1.101 | — | — | 9/23 |
| CASSFGGGGTEAFF | 1.101 | 6/60 | — | — |
| CASSIRGGTLNTEAFF | 1.101 | 2/60 | — | — |
| CASSVRTLDGNTEAFF | 1.101 | 11/60 | — | — |
| CASSPRGASIYF§ | 1.301 | — | 3/10 | 6/23 |
| CASSLARSISGNTIYF | 1.301 | 1/60 | — | — |
| CASSLVGWGQPQHF | 1.501 | 13/60 | — | — |
| CASSLGWGDPNQPQHF | 1.501 | — | 7/10 | — |
| CASSPRTGGSPLHF | 1.602 | — | — | 1/23 |
| CASSMTGELRSPLHF | 1.602 | 2/60 | — | — |
| CASSPGLPGANEQFF | 2.101 | 9/60 | — | — |
| CASSVETGELFF | 2.201 | — | — | 5/23 |
| CASSLPIGTSGGQNIQYF | 2.401 | 6/60 | — | — |
| CASSSQSYEQYF | 2.701 | 5/60 | — | — |
| CASSREVAGGTTSEQYF | 2.701 | 1/60 | — | — |
| CASSLEGGVGRNYEQYF | 2.701 | 3/60 | — | — |
| CASSSQSYEQYF | 2.701 | 1/60 | — | — |
| 8 | ||||
| CASCWRDQYF | 1.101 | 1/15 | — | — |
| CASFGREHYF | 1.101 | 1/15 | — | — |
| CASSAQILDTEAFF | 1.101 | 1/15 | — | — |
| CASGSGPQGYYGYTF | 1.201 | 1/15 | — | — |
| CASSPGTSGSRGEQFF | 2.101 | 4/15 | — | — |
| CASRKQETGELFF | 2.201 | —∥ | — | 10/10 |
| CATGGRASQNTGELFF | 2.201 | 1/15 | — | — |
| CASITVPNTGELFF | 2.201 | 1/15 | — | — |
| CASSLEETQYF | 2.701 | 2/15 | — | — |
| CASSEDTNEQYF | 2.701 | 3/15 | — | — |
| 22 | ||||
| CASSPDRGLNYGYTF | 1.201 | — | 4/9 | — |
| CASSERQGLGYGYTF | 1.201 | — | 1/9 | — |
| CASSIREKSSQPQHF | 1.501 | 1/8 | — | — |
| CASRRLEPDQPQHF | 1.501 | — | 2/9 | — |
| CASREGLAGGNEQFF | 2.101 | 3/8 | — | — |
| CASSGLAGGEDEQFF | 2.101 | 1/8 | — | — |
| CASRVGLVVNTDTQYF | 2.301 | 1/8 | — | — |
| CASSEGTGGSGANVLTF | 2.601 | 1/8 | — | — |
| CASGQGAIFGSYEQYF | 2.701 | — | 2/9 | — |
| CASRMDNYEQYF | 2.701 | 1/8 | — | — |
Specific Vβ family and CDR3* . | Jβ† . | IFNγ+, wk 9‡ . | IFNγ+, wk 53‡ . | CD28-, wk 36‡ . |
|---|---|---|---|---|
| 3 | ||||
| CASSPTSNWGGWTEAFF | 1.101 | 1/4 | — | — |
| CASSLFGLASTDTQYF | 2.301 | — | 7/7 | — |
| CASSLGPAGLAKNIQYF | 2.401 | 1/4 | — | — |
| CASRRGKETQYF | 2.501 | 1/4 | — | — |
| CASKAPLGEQYF | 2.701 | 1/4 | — | — |
| 6.1 | ||||
| CASSKVDTEAFF | 1.101 | — | — | 2/23 |
| CASSTRQGGTEAFF | 1.101 | — | — | 9/23 |
| CASSFGGGGTEAFF | 1.101 | 6/60 | — | — |
| CASSIRGGTLNTEAFF | 1.101 | 2/60 | — | — |
| CASSVRTLDGNTEAFF | 1.101 | 11/60 | — | — |
| CASSPRGASIYF§ | 1.301 | — | 3/10 | 6/23 |
| CASSLARSISGNTIYF | 1.301 | 1/60 | — | — |
| CASSLVGWGQPQHF | 1.501 | 13/60 | — | — |
| CASSLGWGDPNQPQHF | 1.501 | — | 7/10 | — |
| CASSPRTGGSPLHF | 1.602 | — | — | 1/23 |
| CASSMTGELRSPLHF | 1.602 | 2/60 | — | — |
| CASSPGLPGANEQFF | 2.101 | 9/60 | — | — |
| CASSVETGELFF | 2.201 | — | — | 5/23 |
| CASSLPIGTSGGQNIQYF | 2.401 | 6/60 | — | — |
| CASSSQSYEQYF | 2.701 | 5/60 | — | — |
| CASSREVAGGTTSEQYF | 2.701 | 1/60 | — | — |
| CASSLEGGVGRNYEQYF | 2.701 | 3/60 | — | — |
| CASSSQSYEQYF | 2.701 | 1/60 | — | — |
| 8 | ||||
| CASCWRDQYF | 1.101 | 1/15 | — | — |
| CASFGREHYF | 1.101 | 1/15 | — | — |
| CASSAQILDTEAFF | 1.101 | 1/15 | — | — |
| CASGSGPQGYYGYTF | 1.201 | 1/15 | — | — |
| CASSPGTSGSRGEQFF | 2.101 | 4/15 | — | — |
| CASRKQETGELFF | 2.201 | —∥ | — | 10/10 |
| CATGGRASQNTGELFF | 2.201 | 1/15 | — | — |
| CASITVPNTGELFF | 2.201 | 1/15 | — | — |
| CASSLEETQYF | 2.701 | 2/15 | — | — |
| CASSEDTNEQYF | 2.701 | 3/15 | — | — |
| 22 | ||||
| CASSPDRGLNYGYTF | 1.201 | — | 4/9 | — |
| CASSERQGLGYGYTF | 1.201 | — | 1/9 | — |
| CASSIREKSSQPQHF | 1.501 | 1/8 | — | — |
| CASRRLEPDQPQHF | 1.501 | — | 2/9 | — |
| CASREGLAGGNEQFF | 2.101 | 3/8 | — | — |
| CASSGLAGGEDEQFF | 2.101 | 1/8 | — | — |
| CASRVGLVVNTDTQYF | 2.301 | 1/8 | — | — |
| CASSEGTGGSGANVLTF | 2.601 | 1/8 | — | — |
| CASGQGAIFGSYEQYF | 2.701 | — | 2/9 | — |
| CASRMDNYEQYF | 2.701 | 1/8 | — | — |
— indicates not detected.
Amino acid sequence of the retrieved CDR3 sequence.
Corresponding Jβ.
Frequency in which the specific sequence was found in proportion to the total number of clones analyzed for that specific cell population.
Sequences similar in different cell populations.
Similar sequence found in early CMV-specific cells after specific PCR based on sequence found in late CD4+ CD28- population of patient 1.