CDD enzyme activity in bone marrow and spleen cells
. | Bone marrow . | . | Spleen . | . | ||
|---|---|---|---|---|---|---|
. | CDD . | Control . | CDD . | Control . | ||
| Untreated controls | 116 (2) | 4.5 ± 0.4 (3) | 39.1 (2) | 1.6 ± 0.7 (3) | ||
| Animals treated with cytarabine | 401 ± 38 (4) | 2.7 ± 1.2 (3) | 172 ± 33 (4) | 2.7 ± 1.1 (3) | ||
. | Bone marrow . | . | Spleen . | . | ||
|---|---|---|---|---|---|---|
. | CDD . | Control . | CDD . | Control . | ||
| Untreated controls | 116 (2) | 4.5 ± 0.4 (3) | 39.1 (2) | 1.6 ± 0.7 (3) | ||
| Animals treated with cytarabine | 401 ± 38 (4) | 2.7 ± 1.2 (3) | 172 ± 33 (4) | 2.7 ± 1.1 (3) | ||
Mean values ± SEM (when applicable) are given; numbers in parentheses indicate numbers of animals analyzed. CDD indicates CDD vector—transduced cells; control, control vector-transduced cells. CDD enzyme activity (nmol gemcitabine × min-1 × mg protein-1).