Table 1.

Gender distribution of HIT after orthopedic and cardiac surgery


Type of surgery, by sex

No. in Greifswald HIT patient database (%)

No. in German national database (%)
Orthopedic  219   219 663* 
    Female   166 (75.8)   148 355 (67.5)  
    Male   53 (24.2)   71 308 (32.5)  
Cardiac  71   87 302 
    Female   31 (43.7)   25 125 (28.8)  
    Male
 
40 (56.3)
 
62 177 (71.2)
 

Type of surgery, by sex

No. in Greifswald HIT patient database (%)

No. in German national database (%)
Orthopedic  219   219 663* 
    Female   166 (75.8)   148 355 (67.5)  
    Male   53 (24.2)   71 308 (32.5)  
Cardiac  71   87 302 
    Female   31 (43.7)   25 125 (28.8)  
    Male
 
40 (56.3)
 
62 177 (71.2)
 

Orthopedic surgery OR, 1.51 (95% CI, 1.10-2.05; P = .009). Cardiac surgery OR, 1.92 (95% CI, 1.20-3.07; P = .005). Combined surgery OR, 1.61 (95% CI, 1.24-2.08; P = .0003). Controlling for type of surgery (Breslow-Day test for homogeneity), P = .396.

*

2002 data for trauma and elective hip replacement25  and elective knee replacement26  (data for the years preceding 2002 were unavailable).

1997 data for cardiac surgery that included the use of cardiopulmonary bypass; data for patients with congenital heart disease were excluded.27  When all available cardiac surgery data from the nationwide database were used for 1997 to 2002, the results (ratio of female to male) were 31:40 vs 176 500:400 200 (OR, 1.76; 95% CI, 1.10-2.81; P = .017).