Expanded clones detected in marrow biopsies of bone marrow failure patients
Patient no. and CDR3 . | VB . | JB . | % expanded . |
|---|---|---|---|
| 15 | |||
| ASSYSGAPTDT | 13 | 2.3 | 26 |
| ASSIRLGTDT | 14 | 2.3 | 14.8 |
| ASRPSLTSGIYTDT | 14 | 2.3 | 11.1 |
| AISDNNVLTF | 12 | 2.6 | 7.4 |
| ASSVHRGQSYNS | 13 | 1.6 | 7.4 |
| ASSAWGWAASSNE | 17 | 2.1 | 7.4 |
| 30 | |||
| ASSAPQGTDT | 13 | 2.3 | 17.2 |
| 26 | |||
| AIRRVVTDT | 14 | 2.3 | 12 |
| 27 | |||
| ASSQGLAGLTDT | 14 | 2.3 | 26 |
| ASSFSGASDT | 14 | 2.3 | 18.5 |
| ASSPLSRLATDT | 21 | 2.3 | 11.5 |
| ASSYSSHLAGSSYNE | 3 | 2.1 | 7.4 |
| 34 | |||
| ASSEEGWPYG | 13 | 1.2 | 16.6 |
| ASSYSPSYE | 13 | 2.7 | 16.6 |
| 37 | |||
| ASSSIGRTSTDT | 13 | 2.3 | 13 |
| ATSREPYRGPDT | 24 | 2.3 | 8.7 |
| 31 | |||
| ASSYGAGASTDT | 12 | 2.3 | 8 |
| 40 | |||
| ASRETSGHTDT | 14 | 2.3 | 8.7 |
| 16 | |||
| ASSIGDNS | 13 | 1.6 | 10.5 |
| ASSILSEGQP | 4 | 1.3 | 10.5 |
| 18 | |||
| ASSGGTR | 9 | 2.1 | 18.2 |
| 19 | |||
| ASSGGGY | 17 | 2.2 | 25 |
| 39 | |||
| ATRLAGAGDT | 12 | 2.3 | 25 |
| ASSSPPVDT | 6 | 2.3 | 10 |
| ATRRRRKHNE | 15 | 2.1 | 10 |
| 17 | |||
| ASSAGATSTDT | 13 | 2.3 | 14.3 |
| 41 | |||
| ASSKD*REPPRTDT | 10 | 2.3 | 35.7 |
Patient no. and CDR3 . | VB . | JB . | % expanded . |
|---|---|---|---|
| 15 | |||
| ASSYSGAPTDT | 13 | 2.3 | 26 |
| ASSIRLGTDT | 14 | 2.3 | 14.8 |
| ASRPSLTSGIYTDT | 14 | 2.3 | 11.1 |
| AISDNNVLTF | 12 | 2.6 | 7.4 |
| ASSVHRGQSYNS | 13 | 1.6 | 7.4 |
| ASSAWGWAASSNE | 17 | 2.1 | 7.4 |
| 30 | |||
| ASSAPQGTDT | 13 | 2.3 | 17.2 |
| 26 | |||
| AIRRVVTDT | 14 | 2.3 | 12 |
| 27 | |||
| ASSQGLAGLTDT | 14 | 2.3 | 26 |
| ASSFSGASDT | 14 | 2.3 | 18.5 |
| ASSPLSRLATDT | 21 | 2.3 | 11.5 |
| ASSYSSHLAGSSYNE | 3 | 2.1 | 7.4 |
| 34 | |||
| ASSEEGWPYG | 13 | 1.2 | 16.6 |
| ASSYSPSYE | 13 | 2.7 | 16.6 |
| 37 | |||
| ASSSIGRTSTDT | 13 | 2.3 | 13 |
| ATSREPYRGPDT | 24 | 2.3 | 8.7 |
| 31 | |||
| ASSYGAGASTDT | 12 | 2.3 | 8 |
| 40 | |||
| ASRETSGHTDT | 14 | 2.3 | 8.7 |
| 16 | |||
| ASSIGDNS | 13 | 1.6 | 10.5 |
| ASSILSEGQP | 4 | 1.3 | 10.5 |
| 18 | |||
| ASSGGTR | 9 | 2.1 | 18.2 |
| 19 | |||
| ASSGGGY | 17 | 2.2 | 25 |
| 39 | |||
| ATRLAGAGDT | 12 | 2.3 | 25 |
| ASSSPPVDT | 6 | 2.3 | 10 |
| ATRRRRKHNE | 15 | 2.1 | 10 |
| 17 | |||
| ASSAGATSTDT | 13 | 2.3 | 14.3 |
| 41 | |||
| ASSKD*REPPRTDT | 10 | 2.3 | 35.7 |
Stop codon (nonproductive CDR3)