Table 1.

N700S genotype analysis in young survivors of MI


Genotype

Patients no. (%)

Controls no. (%)

OR (95% CI)
AA   1158 (81.3)   1217 (85.4)   —  
AG   250 (17.5)   199 (14.0)   1.4 (1.1-1.8)* 
GG   17 (1.2)   9 (0.6)   1.9 (1.1-3.3)* 
Allele frequency G
 
0.10
 
0.08
 
1.3 (1.1-1.6)
 

Genotype

Patients no. (%)

Controls no. (%)

OR (95% CI)
AA   1158 (81.3)   1217 (85.4)   —  
AG   250 (17.5)   199 (14.0)   1.4 (1.1-1.8)* 
GG   17 (1.2)   9 (0.6)   1.9 (1.1-3.3)* 
Allele frequency G
 
0.10
 
0.08
 
1.3 (1.1-1.6)
 

For patients and controls, N = 1425 each. Unadjusted OR for homozygote (GG) and heterozygote (AG) genotype as compared to the AA genotype estimated under a multiplicative model. Adjusted OR for G allele: 1.4 (95% CI 1.1-1.8; P <.01).

*

P = .01.

P < .01.

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