General angiogenesis genes
. | . | GenBank accession no. . | GAG class . | . | . | No. spots representing GAG . | Library origin§ . | . | . | |
|---|---|---|---|---|---|---|---|---|---|---|
| Gene ID* . | . | . | . | Biologic process† . | Component‡ . | . | HUVEC . | TEC . | CGH∥ . | |
| A kinase (PRKA) anchor protein 13 (AKAP13) | AKAP13 | NM_007200 | A | Signaling | C | 1 | × | — | — | |
| Cathepsin B | CTSB | NM_147783.1 | A | Cellular metabolism | C | 11 | — | × | L8p22 | |
| Caveolin 1, caveolae protein, 22 kDa | CAV1 | NM_001753 | A | Protein regulation | P | 2 | × | G7q31.1 | ||
| CD86 antigen | CD86 | NM_175862 | A | Signaling | P | 1 | — | × | — | |
| cDNA FLJ32199 clone PLACE6002710 | EST | AK056761 | A | Unknown | Unknown | 1 | × | — | ||
| Chemokine (C-C motif) ligand 2 | CCL2 | NM_002982 | A | Signaling | E | 1 | × | — | — | |
| dCMP deaminase | DCTD | NM_001921.1 | A | Cellular metabolism | 1 | × | L4q35.1 | |||
| Defender against cell death 1 | DAD1 | NM_001344 | A | Cellular metabolism | C | 1 | × | — | — | |
| EST10870 HUVEC | EST | AA296386 | A | Unknown | 2 | × | — | — | ||
| Eukaryotic translation initiation factor 4A, isoform 1 | EIF4A1 | NM_001416 | A | Protein regulation | C | 1 | × | — | — | |
| FK506-binding protein 1A, 12 kDa | FKBP1A | NM_000801 | A | Signaling | C | 1 | × | — | G20p13 | |
| FLJ37490 | EST | AK094809.1 | A | Unknown | Unknown | 2 | — | × | — | |
| Heme-binding protein 1 | HEBP1 | NM_015987.2 | A | Cellular metabolism | C | 1 | — | × | — | |
| Hypothetical protein MGC 7036 | MGC7036 | NM_145058 | A | Unknown | Unknown | 1 | — | × | — | |
| IMAGE 2028956 | EST | AI793182 | A | Unknown | Unknown | 1 | × | — | ||
| IMAGE 2096486 | EST | AI422919 | A | Unknown | Unknown | 1 | × | — | ||
| IMAGE 2816112 | EST | AW269823 | A | Unknown | Unknown | 1 | × | — | ||
| Integrin β1 | ITGB1 | NM_002211 | A | Cell surface | P | 1 | × | — | ||
| Isoprenylcysteine carboxyl methyltransferase | ICMT | NM_170705.1 | A | Cellular metabolism | C | 1 | — | × | — | |
| Lung cancer oncogene 5 | HLC5 | AY117690.1 | A | Unknown | Unknown | 1 | × | — | ||
| Major histocompatibility complex, class II, DR α | HLA-DRA | BC032350 | A | Cell surface | P | 24 | × | — | ||
| Matrix metalloproteinase 1, interstitial collagenase | MMP1 | NM_002421 | A | Cellular metabolism | E | 1 | × | — | — | |
| Matrix metalloproteinase 3, stromelysin 1 | MMP3 | NM_002422 | A | Cellular metabolism | E | 1 | — | × | — | |
| Pituitary tumor-transforming 1 interacting protein | PTTG1IP | NM_004339.2 | A | Protein regulation | N | 1 | — | × | — | |
| Rad51-associated protein | RAD51AP1 | NM_006479 | A | Cellular metabolism | N | 1 | × | — | — | |
| Ribosomal protein L22 | RPL22 | NM_000983 | A | Cellular metabolism | C | 1 | × | — | — | |
| Tubulin, α3 | TUBA3 | BC050637 | A | Cytoskeleton organization | C | 1 | × | — | — | |
| v-ral simian leukemia viral oncogene homolog B | RALB | BC018163 | A | Signaling | P | 1 | — | × | — | |
| Androgen-induced 1 | AIG-1 | BC025278 | A,B | Unknown | Unknown | 1 | × | — | — | |
| ATP synthase H+ transporting complex, subunit c | ATP5G1 | NM_001575 | A,B | Protein regulation | C | 1 | × | — | — | |
| Diazepam-binding inhibitor | DBI | M15887 | A,B | Protein regulation | C | 1 | × | — | — | |
| Ectonucleoside triphosphate diphosphohydrolase 1 | ENTPD1 | BC047664 | A,B | Signaling | P | 1 | — | × | — | |
| Endothelial cell-specific molecule 1 | ESM1 | NM_007036 | A,B | Cell growth | E | 1 | × | — | — | |
| Eukaryotic translation elongation factor 1 ϵ1 | EEF1E1 | NM_004280.2 | A,B | Protein regulation | C, N | 2 | × | — | — | |
| Heterogeneous nuclear ribonucleoprotein C (C1/C2) | HNRPC | BC003394 | A,B | Cellular metabolism | N | 1 | × | — | — | |
| HSP90 α | HSP90AA1 | NM_005348 | A,B | Cellular metabolism | Unknown | 1 | × | — | — | |
| IMAGE 757234 | EST | BX115183 | A,B | Unknown | Unknown | 1 | × | — | — | |
| IMAGE 4182080, CARD8 homolog | CARD8 | BC046136 | A,B | Cell growth | N | 1 | × | — | — | |
| Ubiquitin protein ligase E3 component n-recognin 2 | UBR2 | AB002347 | A,B | Protein regulation | N | 1 | — | × | — | |
| Matrix metalloproteinase 10, stromelysin 2 | MMP10 | NM_002425 | A,B | Cellular metabolism | E | 2 | × | — | — | |
| Mitochondrial ribosomal protein S27 | MRPS27 | BC011818 | A,B | Protein regulation | C | 1 | × | — | — | |
| Split hand/foot malformation (ectrodactyly) type 1 | SHFM1 | NM_006304 | A,B | Protein regulation | C | 1 | × | — | G7q21.3 | |
| SRY (sex-determining region Y)-box 4 | SOX4 | NM_003107 | A,B | Transcription | N | 2 | × | — | — | |
| Thymosin, β4, X-linked | TMSB4X | NM_021109 | A,B | Cytoskeleton organization | C | 1 | × | — | — | |
| Ubiquitin-conjugating enzyme E2L3 | UBE2L3 | NM_003347 | A,B | Protein regulation | C | 1 | × | — | — | |
| Zinc finger motif enhancer-binding protein 2 | ZNF644 | NM_032186 | A,B | Transcription | N | 1 | × | — | — | |
| Platelet/endothelial cell adhesion molecule 1 | PECAM1 | NM_000442.2 | B | Cell surface | P | 1 | × | — | — | |
| Ribosomal protein L21 | RPL21 | NM_000982.2 | B | Protein regulation | C | 2 | × | — | G13q12.2 | |
. | . | GenBank accession no. . | GAG class . | . | . | No. spots representing GAG . | Library origin§ . | . | . | |
|---|---|---|---|---|---|---|---|---|---|---|
| Gene ID* . | . | . | . | Biologic process† . | Component‡ . | . | HUVEC . | TEC . | CGH∥ . | |
| A kinase (PRKA) anchor protein 13 (AKAP13) | AKAP13 | NM_007200 | A | Signaling | C | 1 | × | — | — | |
| Cathepsin B | CTSB | NM_147783.1 | A | Cellular metabolism | C | 11 | — | × | L8p22 | |
| Caveolin 1, caveolae protein, 22 kDa | CAV1 | NM_001753 | A | Protein regulation | P | 2 | × | G7q31.1 | ||
| CD86 antigen | CD86 | NM_175862 | A | Signaling | P | 1 | — | × | — | |
| cDNA FLJ32199 clone PLACE6002710 | EST | AK056761 | A | Unknown | Unknown | 1 | × | — | ||
| Chemokine (C-C motif) ligand 2 | CCL2 | NM_002982 | A | Signaling | E | 1 | × | — | — | |
| dCMP deaminase | DCTD | NM_001921.1 | A | Cellular metabolism | 1 | × | L4q35.1 | |||
| Defender against cell death 1 | DAD1 | NM_001344 | A | Cellular metabolism | C | 1 | × | — | — | |
| EST10870 HUVEC | EST | AA296386 | A | Unknown | 2 | × | — | — | ||
| Eukaryotic translation initiation factor 4A, isoform 1 | EIF4A1 | NM_001416 | A | Protein regulation | C | 1 | × | — | — | |
| FK506-binding protein 1A, 12 kDa | FKBP1A | NM_000801 | A | Signaling | C | 1 | × | — | G20p13 | |
| FLJ37490 | EST | AK094809.1 | A | Unknown | Unknown | 2 | — | × | — | |
| Heme-binding protein 1 | HEBP1 | NM_015987.2 | A | Cellular metabolism | C | 1 | — | × | — | |
| Hypothetical protein MGC 7036 | MGC7036 | NM_145058 | A | Unknown | Unknown | 1 | — | × | — | |
| IMAGE 2028956 | EST | AI793182 | A | Unknown | Unknown | 1 | × | — | ||
| IMAGE 2096486 | EST | AI422919 | A | Unknown | Unknown | 1 | × | — | ||
| IMAGE 2816112 | EST | AW269823 | A | Unknown | Unknown | 1 | × | — | ||
| Integrin β1 | ITGB1 | NM_002211 | A | Cell surface | P | 1 | × | — | ||
| Isoprenylcysteine carboxyl methyltransferase | ICMT | NM_170705.1 | A | Cellular metabolism | C | 1 | — | × | — | |
| Lung cancer oncogene 5 | HLC5 | AY117690.1 | A | Unknown | Unknown | 1 | × | — | ||
| Major histocompatibility complex, class II, DR α | HLA-DRA | BC032350 | A | Cell surface | P | 24 | × | — | ||
| Matrix metalloproteinase 1, interstitial collagenase | MMP1 | NM_002421 | A | Cellular metabolism | E | 1 | × | — | — | |
| Matrix metalloproteinase 3, stromelysin 1 | MMP3 | NM_002422 | A | Cellular metabolism | E | 1 | — | × | — | |
| Pituitary tumor-transforming 1 interacting protein | PTTG1IP | NM_004339.2 | A | Protein regulation | N | 1 | — | × | — | |
| Rad51-associated protein | RAD51AP1 | NM_006479 | A | Cellular metabolism | N | 1 | × | — | — | |
| Ribosomal protein L22 | RPL22 | NM_000983 | A | Cellular metabolism | C | 1 | × | — | — | |
| Tubulin, α3 | TUBA3 | BC050637 | A | Cytoskeleton organization | C | 1 | × | — | — | |
| v-ral simian leukemia viral oncogene homolog B | RALB | BC018163 | A | Signaling | P | 1 | — | × | — | |
| Androgen-induced 1 | AIG-1 | BC025278 | A,B | Unknown | Unknown | 1 | × | — | — | |
| ATP synthase H+ transporting complex, subunit c | ATP5G1 | NM_001575 | A,B | Protein regulation | C | 1 | × | — | — | |
| Diazepam-binding inhibitor | DBI | M15887 | A,B | Protein regulation | C | 1 | × | — | — | |
| Ectonucleoside triphosphate diphosphohydrolase 1 | ENTPD1 | BC047664 | A,B | Signaling | P | 1 | — | × | — | |
| Endothelial cell-specific molecule 1 | ESM1 | NM_007036 | A,B | Cell growth | E | 1 | × | — | — | |
| Eukaryotic translation elongation factor 1 ϵ1 | EEF1E1 | NM_004280.2 | A,B | Protein regulation | C, N | 2 | × | — | — | |
| Heterogeneous nuclear ribonucleoprotein C (C1/C2) | HNRPC | BC003394 | A,B | Cellular metabolism | N | 1 | × | — | — | |
| HSP90 α | HSP90AA1 | NM_005348 | A,B | Cellular metabolism | Unknown | 1 | × | — | — | |
| IMAGE 757234 | EST | BX115183 | A,B | Unknown | Unknown | 1 | × | — | — | |
| IMAGE 4182080, CARD8 homolog | CARD8 | BC046136 | A,B | Cell growth | N | 1 | × | — | — | |
| Ubiquitin protein ligase E3 component n-recognin 2 | UBR2 | AB002347 | A,B | Protein regulation | N | 1 | — | × | — | |
| Matrix metalloproteinase 10, stromelysin 2 | MMP10 | NM_002425 | A,B | Cellular metabolism | E | 2 | × | — | — | |
| Mitochondrial ribosomal protein S27 | MRPS27 | BC011818 | A,B | Protein regulation | C | 1 | × | — | — | |
| Split hand/foot malformation (ectrodactyly) type 1 | SHFM1 | NM_006304 | A,B | Protein regulation | C | 1 | × | — | G7q21.3 | |
| SRY (sex-determining region Y)-box 4 | SOX4 | NM_003107 | A,B | Transcription | N | 2 | × | — | — | |
| Thymosin, β4, X-linked | TMSB4X | NM_021109 | A,B | Cytoskeleton organization | C | 1 | × | — | — | |
| Ubiquitin-conjugating enzyme E2L3 | UBE2L3 | NM_003347 | A,B | Protein regulation | C | 1 | × | — | — | |
| Zinc finger motif enhancer-binding protein 2 | ZNF644 | NM_032186 | A,B | Transcription | N | 1 | × | — | — | |
| Platelet/endothelial cell adhesion molecule 1 | PECAM1 | NM_000442.2 | B | Cell surface | P | 1 | × | — | — | |
| Ribosomal protein L21 | RPL21 | NM_000982.2 | B | Protein regulation | C | 2 | × | — | G13q12.2 | |
Extracellular matrix indicates ECM organization and biosynthesis; cell surface, cell-surface receptor-linked signal transduction, antigen presentation; transcription, regulation of transcription; cytoskeleton organization, cytoskeleton organization and biogenesis; cell growth, regulation of cell growth, cell cycle, apoptosis; protein regulation, cellular protein metabolism, protein biosynthesis, translation, transport; C, cytoplasm; N, nucleus; P, plasma membrane; E, extracellular; CGH, comparative genomic hybridization; and —, not applicable.
Sequence identity.
Functional classification of the reported GAG, inferred from Gene Ontology Database.
Cellular component of the reported GAG, inferred from Gene Ontology Database.
SSH cDNA repertoire origin of the spots.
Progenetix large intestine database (www.progenetix.de). G indicates gain; L, loss; defined by 15% difference in aberrations per band.