Table 5.

Correlation of metaphase cytogenetics to the IgVH status and CD38 expression



IgVH

CD38
No. Patients
No. Patients
Metaphase cytogenetics
M
UM
P
Negative
Positive
P
At least 3 aberrations   8   16   .122   13   12   .018  
At least 3 unbalanced aberrations   8   13   .35   12   9   .126  
Translocations*  9   24   .006   19   14   .045  
Unbalanced translocations  4   17   .004   14   5   .757  
Balanced translocations
 
9
 
11
 
.82
 
10
 
11
 
.009
 


IgVH

CD38
No. Patients
No. Patients
Metaphase cytogenetics
M
UM
P
Negative
Positive
P
At least 3 aberrations   8   16   .122   13   12   .018  
At least 3 unbalanced aberrations   8   13   .35   12   9   .126  
Translocations*  9   24   .006   19   14   .045  
Unbalanced translocations  4   17   .004   14   5   .757  
Balanced translocations
 
9
 
11
 
.82
 
10
 
11
 
.009
 

For IgVHM, n = 52; for UM, n = 58. For CD38-negative, n = 75; for CD38-positive, n = 31.

*

Nine samples had balanced as well as unbalanced translocations.

Including samples with balanced or unbalanced translocations in parallel.

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