Recurrent breakpoints, and genes that are involved in such breakpoints in leukemia29 ,33
Breakpoints . | No. . | Genes . |
|---|---|---|
| 1p36 | 2 | MDS2 |
| 1q21 | 2 | AF1q, BCL9, IRTA1, MUC1 |
| 2p13 | 2 | BCL11A |
| 2q37 | 2 | Unknown |
| 7p11 | 2 | Unknown |
| 7q11.2 | 2 | HIP1 |
| 8p21 | 2 | Unknown |
| 8q24 | 2 | C-MYC |
| 9q34 | 2 | ABL, AF9q34, CAN, FBP17, NOTCH1, PRRX2 |
| 12p13 | 2 | ETV6 |
| 13q22 | 2 | Unknown |
| 15q10 | 2 | Unknown |
| 17q23 | 2 | CLTC, MSI2 |
| 18p11.3 | 2 | Unknown |
| 19q13 | 2 | BCL3 |
| 20p11 | 2 | Unknown |
| 22q10 | 2 | Unknown |
| 7p15 | 3 | HOXA9, HOXA10 |
| 10q24 | 3 | HOX 11 |
| 16q24 | 3 | CBFA2T3 |
| 17q10 | 3 | Unknown |
| 17q21 | 3 | RARA |
| 18p11 | 3 | Unknown |
| 18q21 | 3 | BCL2, MALT1 |
| 20q11 | 3 | TOP1 |
| 2p11 | 4 | Unknown |
| 11q13 | 4 | CCND1 |
| 13q14 | 7 | MIRN15A, MIRN16-1 |
| 14q32 | 7 | IGH |
Breakpoints . | No. . | Genes . |
|---|---|---|
| 1p36 | 2 | MDS2 |
| 1q21 | 2 | AF1q, BCL9, IRTA1, MUC1 |
| 2p13 | 2 | BCL11A |
| 2q37 | 2 | Unknown |
| 7p11 | 2 | Unknown |
| 7q11.2 | 2 | HIP1 |
| 8p21 | 2 | Unknown |
| 8q24 | 2 | C-MYC |
| 9q34 | 2 | ABL, AF9q34, CAN, FBP17, NOTCH1, PRRX2 |
| 12p13 | 2 | ETV6 |
| 13q22 | 2 | Unknown |
| 15q10 | 2 | Unknown |
| 17q23 | 2 | CLTC, MSI2 |
| 18p11.3 | 2 | Unknown |
| 19q13 | 2 | BCL3 |
| 20p11 | 2 | Unknown |
| 22q10 | 2 | Unknown |
| 7p15 | 3 | HOXA9, HOXA10 |
| 10q24 | 3 | HOX 11 |
| 16q24 | 3 | CBFA2T3 |
| 17q10 | 3 | Unknown |
| 17q21 | 3 | RARA |
| 18p11 | 3 | Unknown |
| 18q21 | 3 | BCL2, MALT1 |
| 20q11 | 3 | TOP1 |
| 2p11 | 4 | Unknown |
| 11q13 | 4 | CCND1 |
| 13q14 | 7 | MIRN15A, MIRN16-1 |
| 14q32 | 7 | IGH |