Table 1.

Patient characteristics


Characteristic

Data
Sex, no. patients  
    Male   16  
    Female   13  
Median age, y (range)   73 (67-82)  
Median ECOG performance status, (range)   1 (1-3)  
Median d from diagnosis to trial entry (range)   21 (6-166)  
FAB type, no. patients  
    MO   2  
    M1   7  
    M2   7  
    M4   6  
    M5   1  
    M6   3  
    Not classified   3  
Cytogenetic risk group, no. patients  
    Adverse   5  
    Intermediate   23  
    Favorable   1  
FLT3 mutation status, no. patients  
    Internal tandem duplication mutation   2  
    Tyrosine kinase domain mutation   3  
    Wild type   24  
Median presenting WBC count, × 109/L (range)   6.1 (0.8-140.7)  
Prior therapy, no. patients  
    Oral hydroxyurea   5  
    No prior treatment
 
24
 

Characteristic

Data
Sex, no. patients  
    Male   16  
    Female   13  
Median age, y (range)   73 (67-82)  
Median ECOG performance status, (range)   1 (1-3)  
Median d from diagnosis to trial entry (range)   21 (6-166)  
FAB type, no. patients  
    MO   2  
    M1   7  
    M2   7  
    M4   6  
    M5   1  
    M6   3  
    Not classified   3  
Cytogenetic risk group, no. patients  
    Adverse   5  
    Intermediate   23  
    Favorable   1  
FLT3 mutation status, no. patients  
    Internal tandem duplication mutation   2  
    Tyrosine kinase domain mutation   3  
    Wild type   24  
Median presenting WBC count, × 109/L (range)   6.1 (0.8-140.7)  
Prior therapy, no. patients  
    Oral hydroxyurea   5  
    No prior treatment
 
24
 

FAB indicates French-American-British classification.

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