Table 7.

Long-term outcome of non-Stx–HUS patients




No mutation, no.

CFH mutation, no.

MCP mutation, no.

IF mutation, no.

P1

P2

P3
Patients with remission  36 (84)   9 (40)   12 (14)   2 (6)   .03  .007  <.001 
    Patients with complete remission   22 (36)   3 (9)   4 (12)   2 (2)   .13   .09   >.999 
    Patients with complete remission, after recurrences   14 (36)   6 (9)   8 (12)   0 (2)   .13   .09   >.999 
Patients with no remission  48 (84)   31 (40)   2 (14)   4 (6)   .03  .003  <.001 
    Chronic renal insufficiency   5 (48)   3 (31)   0 (2)   0 (4)   .91   .63   .64  
    ESRF   32 (48)   13 (31)   2 (2)   4 (4)   .03  .32   .29 
    Death
 
11 (48)
 
15 (31)
 
0 (2)
 
0 (4)
 
.019
 
.44
 
.18
 



No mutation, no.

CFH mutation, no.

MCP mutation, no.

IF mutation, no.

P1

P2

P3
Patients with remission  36 (84)   9 (40)   12 (14)   2 (6)   .03  .007  <.001 
    Patients with complete remission   22 (36)   3 (9)   4 (12)   2 (2)   .13   .09   >.999 
    Patients with complete remission, after recurrences   14 (36)   6 (9)   8 (12)   0 (2)   .13   .09   >.999 
Patients with no remission  48 (84)   31 (40)   2 (14)   4 (6)   .03  .003  <.001 
    Chronic renal insufficiency   5 (48)   3 (31)   0 (2)   0 (4)   .91   .63   .64  
    ESRF   32 (48)   13 (31)   2 (2)   4 (4)   .03  .32   .29 
    Death
 
11 (48)
 
15 (31)
 
0 (2)
 
0 (4)
 
.019
 
.44
 
.18
 

IF mutation group has not been included in statistical analysis. The numbers of patients for whom data were available are reported in parentheses.

P1 indicates no mutation versus CFH mutation; P2, no mutation versus MCP mutation; and P3, CFH mutation versus MCP mutation.

Close Modal

or Create an Account

Close Modal
Close Modal