Table 1.
Effect of Gardos channel inhibitors on platelet aggregation and release
.
Aggregation, % control ± SD
.
Release (ATP), % control ± SD
.
120 mM high K
+
100.8 ± 6.0
79.4 ± 3.3
10 μM clotrimazol
90.0 ± 2.8
91.3 ± 5.0
20 nM charybdotoxin
108.3 ± 10.2
98.7 ± 9.0
0.4 mM quinine
40.0 ± 3.0
90.1 ± 4.1
.
Aggregation, % control ± SD
.
Release (ATP), % control ± SD
.
120 mM high K
+
100.8 ± 6.0
79.4 ± 3.3
10 μM clotrimazol
90.0 ± 2.8
91.3 ± 5.0
20 nM charybdotoxin
108.3 ± 10.2
98.7 ± 9.0
0.4 mM quinine
40.0 ± 3.0
90.1 ± 4.1
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