Table 1.

Effect of Gardos channel inhibitors on platelet aggregation and release




Aggregation, % control ± SD

Release (ATP), % control ± SD
120 mM high K+  100.8 ± 6.0   79.4 ± 3.3  
10 μM clotrimazol   90.0 ± 2.8   91.3 ± 5.0  
20 nM charybdotoxin   108.3 ± 10.2   98.7 ± 9.0  
0.4 mM quinine
 
40.0 ± 3.0
 
90.1 ± 4.1
 



Aggregation, % control ± SD

Release (ATP), % control ± SD
120 mM high K+  100.8 ± 6.0   79.4 ± 3.3  
10 μM clotrimazol   90.0 ± 2.8   91.3 ± 5.0  
20 nM charybdotoxin   108.3 ± 10.2   98.7 ± 9.0  
0.4 mM quinine
 
40.0 ± 3.0
 
90.1 ± 4.1
 
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