Characteristics of the 61 patients analyzed
Characteristic . | Value* . |
|---|---|
| Sex, no. M/no. F patients | 32/29 |
| Median age at transplantation, y (range) | 9 (1-24) |
| Underlying disease | |
| Malignant | 37 (61) |
| Nonmalignant | 24 (39) |
| Stem-cell source | |
| Bone marrow | 43 (70) |
| Peripheral blood | 14 (23) |
| Cord blood | 4 (7) |
| Donor type | |
| Sibling | 22 (36) |
| Unrelated | 27 (44) |
| Haploidentical relative | 12 (20) |
| Donor/recipient HCMV serostatus | |
| D+/R+ | 28 (46) |
| D-/R+ | 11 (18) |
| D+/R- | 18 (29) |
| D-/R- | 4 (7) |
| Conditioning regimen | |
| TBI based | 27 (44) |
| Non-TBI based | 34 (56) |
| GvHD prophylaxis | |
| CS-A | 13 (21) |
| CS-A + MTX | 36 (59) |
| T-cell depletion | 12 (20) |
| Administration of ALG | |
| Yes | 27 (44) |
| No | 34 (56) |
| GvHD grade | |
| 0 to I | 44 (72) |
| II to IV | 17 (28) |
| Steroid therapy | |
| Yes | 26 (43) |
| No | 35 (57) |
Characteristic . | Value* . |
|---|---|
| Sex, no. M/no. F patients | 32/29 |
| Median age at transplantation, y (range) | 9 (1-24) |
| Underlying disease | |
| Malignant | 37 (61) |
| Nonmalignant | 24 (39) |
| Stem-cell source | |
| Bone marrow | 43 (70) |
| Peripheral blood | 14 (23) |
| Cord blood | 4 (7) |
| Donor type | |
| Sibling | 22 (36) |
| Unrelated | 27 (44) |
| Haploidentical relative | 12 (20) |
| Donor/recipient HCMV serostatus | |
| D+/R+ | 28 (46) |
| D-/R+ | 11 (18) |
| D+/R- | 18 (29) |
| D-/R- | 4 (7) |
| Conditioning regimen | |
| TBI based | 27 (44) |
| Non-TBI based | 34 (56) |
| GvHD prophylaxis | |
| CS-A | 13 (21) |
| CS-A + MTX | 36 (59) |
| T-cell depletion | 12 (20) |
| Administration of ALG | |
| Yes | 27 (44) |
| No | 34 (56) |
| GvHD grade | |
| 0 to I | 44 (72) |
| II to IV | 17 (28) |
| Steroid therapy | |
| Yes | 26 (43) |
| No | 35 (57) |
TBI indicates total body irradiation; CS-A, cyclosporine-A; MTX, methotrexate; ALG, antilymphocyte globulin; and GvHD, graft-versus-host disease.
Values are expressed as number of patients (percent of patients) unless otherwise indicated.