Table 1. Summary of data from patient... | American Society of Hematology

Table 1.

Summary of data from patient with informative clonality assays

UPN	Dx	Sex	Age, y	Disease duration, mo	GRA V617F status	9p LOH	GRA AS-PCR, %T	GRA SNaPshot, %T	PLT SNaPshot, %T	Clonality marker	Clonality status	Clonal cells, %	T-cell clonality	20q LOH
p138	PV	F	70	0	-	-	0	—	—	MPP1	Clonal	100	—	-
p115	PV	F	90	127	+	-	7	7	—	MPP1	Clonal	100	Skewed	+
p099	PV	F	66	21	+	-	9	6	17	MPP1	Clonal	92	Poly	-
p022	PV	F	28	12	+	-	35	—	—	IDS	Clonal	71	Poly	-
p062	PV	F	82	3	+	+	53	—	—	IDS	Clonal	89	—	-
p046	PV	F	69	77	+	+	56	—	—	MPP1	Clonal	100	—	-
p008	PV	F	44	—	+	+	69	—	—	IDS	Clonal	90	—	-
p088	PV	F	62	129	+	+	72	—	—	IDS	Clonal	90	—	-
p148	PV	F	38	107	+	+	74	—	—	MPP1	Clonal	100	—	-
p126	PV	F	61	171	+	+	84	—	—	MPP1	Clonal	100	—	-
p009	PV	F	68	—	+	+	90	—	—	MPP1	Clonal	94	—	-
p103	PV	F	80	576	+	+	95	—	—	IDS	Clonal	100	—	+
p011	ET	F	28	5	-	-	0	—	—	MPP1	Clonal	84	—	-
p042	ET	F	76	0	-	-	0	—	—	MPP1	Clonal	85	—	-
p084	ET	F	15	0	-	-	0	—	—	MPP1	Poly	39	—	-
p134	ET	F	32	4	-	-	0	—	—	MPP1	Poly	66	—	-
p151	ET	F	32	1	-	-	0	—	—	IDS	Poly	23	—	-
p089	ET	F	42	0	+	-	7	—	12	MPP1	Clonal	95	Poly	-
p119	ET	F	29	15	+	-	8	—	—	IDS	Poly	67	Poly	-
p162	ET	F	67	51	+	-	8	—	—	IDS	Poly	26	Poly	-
p125	ET	F	66	0	+	-	9	6	8	IDS	Clonal	97	Poly	-
p170	ET	F	80	0	+	-	14	11	—	IDS	Poly	14	—	-
p015	ET	F	59	49	+	-	14	8	7	IDS	Clonal	77	Skewed	-
p114	ET	F	56	227	+	-	20	21	4	MPP1	Clonal	86	Poly	-
p113	ET	F	67	114	+	-	23	18	6	MPP1	Clonal	93	—	-
CA71	ET	M	43	11	+	-	7	—	—	—	Clonal	—	—	+
p102	IMF	F	43	0	-	-	0	—	—	MPP1	Clonal	76	—	-
p146	IMF	F	35	56	-	-	0	—	—	IDS	Poly	17	—	-
p050	IMF	F	27	58	+	+	92	—	—	IDS	Clonal	100	—	-

UPN	Dx	Sex	Age, y	Disease duration, mo	GRA V617F status	9p LOH	GRA AS-PCR, %T	GRA SNaPshot, %T	PLT SNaPshot, %T	Clonality marker	Clonality status	Clonal cells, %	T-cell clonality	20q LOH
p138	PV	F	70	0	-	-	0	—	—	MPP1	Clonal	100	—	-
p115	PV	F	90	127	+	-	7	7	—	MPP1	Clonal	100	Skewed	+
p099	PV	F	66	21	+	-	9	6	17	MPP1	Clonal	92	Poly	-
p022	PV	F	28	12	+	-	35	—	—	IDS	Clonal	71	Poly	-
p062	PV	F	82	3	+	+	53	—	—	IDS	Clonal	89	—	-
p046	PV	F	69	77	+	+	56	—	—	MPP1	Clonal	100	—	-
p008	PV	F	44	—	+	+	69	—	—	IDS	Clonal	90	—	-
p088	PV	F	62	129	+	+	72	—	—	IDS	Clonal	90	—	-
p148	PV	F	38	107	+	+	74	—	—	MPP1	Clonal	100	—	-
p126	PV	F	61	171	+	+	84	—	—	MPP1	Clonal	100	—	-
p009	PV	F	68	—	+	+	90	—	—	MPP1	Clonal	94	—	-
p103	PV	F	80	576	+	+	95	—	—	IDS	Clonal	100	—	+
p011	ET	F	28	5	-	-	0	—	—	MPP1	Clonal	84	—	-
p042	ET	F	76	0	-	-	0	—	—	MPP1	Clonal	85	—	-
p084	ET	F	15	0	-	-	0	—	—	MPP1	Poly	39	—	-
p134	ET	F	32	4	-	-	0	—	—	MPP1	Poly	66	—	-
p151	ET	F	32	1	-	-	0	—	—	IDS	Poly	23	—	-
p089	ET	F	42	0	+	-	7	—	12	MPP1	Clonal	95	Poly	-
p119	ET	F	29	15	+	-	8	—	—	IDS	Poly	67	Poly	-
p162	ET	F	67	51	+	-	8	—	—	IDS	Poly	26	Poly	-
p125	ET	F	66	0	+	-	9	6	8	IDS	Clonal	97	Poly	-
p170	ET	F	80	0	+	-	14	11	—	IDS	Poly	14	—	-
p015	ET	F	59	49	+	-	14	8	7	IDS	Clonal	77	Skewed	-
p114	ET	F	56	227	+	-	20	21	4	MPP1	Clonal	86	Poly	-
p113	ET	F	67	114	+	-	23	18	6	MPP1	Clonal	93	—	-
CA71	ET	M	43	11	+	-	7	—	—	—	Clonal	—	—	+
p102	IMF	F	43	0	-	-	0	—	—	MPP1	Clonal	76	—	-
p146	IMF	F	35	56	-	-	0	—	—	IDS	Poly	17	—	-
p050	IMF	F	27	58	+	+	92	—	—	IDS	Clonal	100	—	-

The percentages of JAK2-V617F (%T), IDS, and MPP1 were calculated as described in “Patients” and in Figure 1. Note that the presence of 9p LOH correlates with %T greater than 50%.

UPN indicates unique patient number; Dx, diagnosis; 9p LOH, loss of heterozygosity on chromosome 9p; 20q LOH, loss of heterozygosity on chromosome 20q; F, female; -, absence; —, not available; +, presence; Poly, polyclonal; and M, male.

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