Genes with unique gene-expression profile in WM
Probe . | P . | Gene names . | Fold change relative to MM . | Fold change relative to CLL . | Descriptions . | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Up-regulated in WM compared with CLL and MM | ||||||||||
| 205207_at | < .001 | IL6 | 4.39 | 6.41 | Interleukin 6 (interferon-β2) | |||||
| 204081_at | < .001 | NRGN | 3.23 | 5.38 | Neurogranin (protein kinase C substrate, RC3) | |||||
| 201310_s_at | < .001 | P311 | 4.9 | 6.29 | P311 protein | |||||
| 209626_s_at | < .001 | OSBPL3 | 3.63 | 2.77 | Oxysterol binding protein-like 3 | |||||
| 205987_at | < .001 | CD1C | 24.4 | 17.99 | CD1C antigen, c polypeptide | |||||
| 210640_s_at | < .001 | GPR30 | 9.75 | 8.93 | G protein-coupled receptor 30 | |||||
| 205240_at | < .001 | HSU54999 | 2.28 | 3.66 | LGN protein | |||||
| 211829_s_at | < .001 | GPR30 | 6.08 | 8.93 | G protein–coupled receptor 30 | |||||
| 202497_x_at | < .001 | SLC2A3 | 7.55 | 4.39 | Solute carrier family 2 (facilitated glucose transporter), member 3 | |||||
| 215464_s_at | < .001 | TIP-1 | 4.1 | 4.85 | Tax interaction protein 1 | |||||
| 209053_s_at | .004 | WHSC1 | 3.12 | 2.94 | Wolf-Hirschhorn syndrome candidate 1 | |||||
| Down-regulated in WM compared with CLL and MM | ||||||||||
| 222154_s_at | < .001 | DKFZP564 A2416 | 6.33 | 6.64 | DKFZP564A2416 protein | |||||
| 219878_s_at | < .001 | KLF13 | 5.99 | 6.04 | Kruppel-like factor 13 | |||||
| 221163_s_at | < .001 | WBSCR14 | 3.39 | 4.58 | Williams-Beuren syndrome critical region gene 14 | |||||
| 216869_at | < .001 | PDE1C | 2.42 | 3.21 | PDE1C3 splice variant; 3′,5′ cyclic nucleotide phosphodiesterase | |||||
| 218182_s_at | < .001 | CLDN1 | 2.05 | 3.55 | Claudin 1 | |||||
| 219630_at | < .001 | DD96 | 2.16 | 3.22 | Epithelial protein up-regulated in carcinoma, membrane-associated protein 17 | |||||
| 206736_x_at | < .001 | CHRNA4 | 3.09 | 3.75 | Cholinergic receptor, nicotinic, α-polypeptide 4 | |||||
| 206994_at | < .001 | CST4 | 3.24 | 2.97 | Cystatin S | |||||
| 215967_s_at | < .001 | LY9 | 3.27 | 2.93 | Lymphocyte antigen 9 | |||||
| 207553_at | < .001 | OPRK1 | 3.88 | 3.09 | Opioid receptor, κ1 | |||||
Probe . | P . | Gene names . | Fold change relative to MM . | Fold change relative to CLL . | Descriptions . | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Up-regulated in WM compared with CLL and MM | ||||||||||
| 205207_at | < .001 | IL6 | 4.39 | 6.41 | Interleukin 6 (interferon-β2) | |||||
| 204081_at | < .001 | NRGN | 3.23 | 5.38 | Neurogranin (protein kinase C substrate, RC3) | |||||
| 201310_s_at | < .001 | P311 | 4.9 | 6.29 | P311 protein | |||||
| 209626_s_at | < .001 | OSBPL3 | 3.63 | 2.77 | Oxysterol binding protein-like 3 | |||||
| 205987_at | < .001 | CD1C | 24.4 | 17.99 | CD1C antigen, c polypeptide | |||||
| 210640_s_at | < .001 | GPR30 | 9.75 | 8.93 | G protein-coupled receptor 30 | |||||
| 205240_at | < .001 | HSU54999 | 2.28 | 3.66 | LGN protein | |||||
| 211829_s_at | < .001 | GPR30 | 6.08 | 8.93 | G protein–coupled receptor 30 | |||||
| 202497_x_at | < .001 | SLC2A3 | 7.55 | 4.39 | Solute carrier family 2 (facilitated glucose transporter), member 3 | |||||
| 215464_s_at | < .001 | TIP-1 | 4.1 | 4.85 | Tax interaction protein 1 | |||||
| 209053_s_at | .004 | WHSC1 | 3.12 | 2.94 | Wolf-Hirschhorn syndrome candidate 1 | |||||
| Down-regulated in WM compared with CLL and MM | ||||||||||
| 222154_s_at | < .001 | DKFZP564 A2416 | 6.33 | 6.64 | DKFZP564A2416 protein | |||||
| 219878_s_at | < .001 | KLF13 | 5.99 | 6.04 | Kruppel-like factor 13 | |||||
| 221163_s_at | < .001 | WBSCR14 | 3.39 | 4.58 | Williams-Beuren syndrome critical region gene 14 | |||||
| 216869_at | < .001 | PDE1C | 2.42 | 3.21 | PDE1C3 splice variant; 3′,5′ cyclic nucleotide phosphodiesterase | |||||
| 218182_s_at | < .001 | CLDN1 | 2.05 | 3.55 | Claudin 1 | |||||
| 219630_at | < .001 | DD96 | 2.16 | 3.22 | Epithelial protein up-regulated in carcinoma, membrane-associated protein 17 | |||||
| 206736_x_at | < .001 | CHRNA4 | 3.09 | 3.75 | Cholinergic receptor, nicotinic, α-polypeptide 4 | |||||
| 206994_at | < .001 | CST4 | 3.24 | 2.97 | Cystatin S | |||||
| 215967_s_at | < .001 | LY9 | 3.27 | 2.93 | Lymphocyte antigen 9 | |||||
| 207553_at | < .001 | OPRK1 | 3.88 | 3.09 | Opioid receptor, κ1 | |||||
The top 10 up- and down-regulated genes plus other genes of interest are shown