Allele and genotype frequency of the BCL6397G/C polymorphism in 120 DLBCLs, 95 FLs, and 230 control subjects
. | Controls, N = 230 . | DLBCL total, n = 120 . | GC DLBCL, n = 55 . | Non-GC DLBCL, n = 65 . | FL total, n = 95 . | Transformed FL, n = 56 . | Nontransformed FL, n = 39 (%) . | P, controls versus GC . | P, controls versus non-GC . | P, GC versus non-GC . |
|---|---|---|---|---|---|---|---|---|---|---|
| Allele frequency | .005* | .07 | <.001* | |||||||
| BCL6397G | 0.90 | 0.89 | 0.81 | 0.95 | 0.90 | 0.88 | 0.92 | |||
| BCL6397C | 0.10 | 0.11 | 0.19 | 0.05 | 0.10 | 0.12 | 0.08 | |||
| Genotype frequency | .02* | .08 | .001* | |||||||
| BCL6397GG, no. (%) | 188 (82) | 96 (80) | 37 (67) | 59 (91) | 77 (81) | 44 (79) | 33 (85) | |||
| BCL6397GC, no. (%) | 40 (17) | 21 (18) | 15 (27) | 6 (9) | 17 (18) | 11 (20) | 6 (15) | |||
| BCL6397CC, no. (%) | 2 (1) | 3 (2) | 3 (5) | 0 (0) | 1 (1) | 1 (2) | 0 (0) |
. | Controls, N = 230 . | DLBCL total, n = 120 . | GC DLBCL, n = 55 . | Non-GC DLBCL, n = 65 . | FL total, n = 95 . | Transformed FL, n = 56 . | Nontransformed FL, n = 39 (%) . | P, controls versus GC . | P, controls versus non-GC . | P, GC versus non-GC . |
|---|---|---|---|---|---|---|---|---|---|---|
| Allele frequency | .005* | .07 | <.001* | |||||||
| BCL6397G | 0.90 | 0.89 | 0.81 | 0.95 | 0.90 | 0.88 | 0.92 | |||
| BCL6397C | 0.10 | 0.11 | 0.19 | 0.05 | 0.10 | 0.12 | 0.08 | |||
| Genotype frequency | .02* | .08 | .001* | |||||||
| BCL6397GG, no. (%) | 188 (82) | 96 (80) | 37 (67) | 59 (91) | 77 (81) | 44 (79) | 33 (85) | |||
| BCL6397GC, no. (%) | 40 (17) | 21 (18) | 15 (27) | 6 (9) | 17 (18) | 11 (20) | 6 (15) | |||
| BCL6397CC, no. (%) | 2 (1) | 3 (2) | 3 (5) | 0 (0) | 1 (1) | 1 (2) | 0 (0) |
P values were calculated using χ2 test. The P value for the genotype frequency is calculated for BCL6397GG versus BCL6397CG/CC
Significant values