HSC chimerism in the bone marrow of engrafted mice
Recipient mice . | No. of mice . | Degree of macrophage chimerism, % range . |
|---|---|---|
| Rag2° | 3 | 0.15-0.31 |
| Rag°γc° | 5 | 0.24-0.37 |
| Rag2°IL2Rβ° | 3 | 0.30-1.21 |
| Flt3°IL7Rα° | 3 | 5.92-9.16 |
Recipient mice . | No. of mice . | Degree of macrophage chimerism, % range . |
|---|---|---|
| Rag2° | 3 | 0.15-0.31 |
| Rag°γc° | 5 | 0.24-0.37 |
| Rag2°IL2Rβ° | 3 | 0.30-1.21 |
| Flt3°IL7Rα° | 3 | 5.92-9.16 |
Mice were analyzed 10 weeks after bone marrow transplantation with sorted Lin-cKit+Sca1+ cells from wild-type C57BI/6Ly5.1 mice. Donor macrophages, which express CD45.1, can be distinguished from recipient macrophages, which express CD45.2. The degree of chimerism expressed in percentage is calculated as follows: CD45.1+CD11b+/CD11b+ (CD45.1+ plus CD45.2+).